Rabbit Anti-APP Antibody (MO-DKB-00491W)
Cat: MO-DKB-00491W
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- Product Details
Specifications
| Host species | Rabbit (Oryctolagus cuniculus) |
| Species Reactivity | Human (Homo sapiens), Mouse (Mus musculus), Dog (Canis lupus familiaris), Fruit fly (Drosophila melanogaster) |
| Immunogen | Synthetic peptide corresponding to the starting point of the N-terminal 3-pyro E of human amyloid β. |
| Epitope | The epitope is in the N-terminal of APP. |
| Format | Liquid or Lyophilized |
| Buffer | 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | Affinity purified |
Application Information
| Application | WB, ELISA, IA, IF, IHC, IHC-Fr |
| Application Notes | Western Blot 1 ug/ml ELISA 1:20000-1:60000 Immunoassay Immunocytochemistry/Immunofluorescence 1:100-1:500 Immunohistochemistry 1:100-1:500 |
Target
| Introduction | This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Aug 2014] |
| Product Overview | This product is a Rabbit antibody against the N-terminal of the APP. It can be used for APP detection in Western Blot, Enzyme-Linked Immunosorbent Assay, IA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen. |
| Alternative Names | Amyloid Beta Precursor Protein; Amyloid Beta (A4) Precursor Protein; Alzheimer Disease Amyloid Protein; Cerebral Vascular Amyloid Peptide; Amyloid Precursor Protein; Peptidase Nexin-II; Protease Nexin-II; PreA4; PN-II; ABPP; APPI; CVAP; AD1; Beta-Amyloid Precursor Protein; |
| Gene ID | 351 |
| UniProt ID | P05067 |
See other products for " app "
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| MO-AB-08377W | Mouse Anti-Cat APP Antibody (MO-AB-08377W) |
| MO-AB-43697W | Mouse Anti-Horse APP Antibody (MO-AB-43697W) |
| MO-AB-29002W | Mouse Anti-Dog APP Antibody (MO-AB-29002W) |
| MO-AB-24129H | Mouse Anti-Rat APP Antibody (MO-AB-24129H) |
| MO-AB-07514R | Mouse Anti-Cattle APP Antibody (MO-AB-07514R) |
| CBMOAB-36084FYA | Mouse Anti-Rhesus APP Antibody (CBMOAB-36084FYA) |
| MO-AB-01096W | Mouse Anti-Rhesus APP Antibody (MO-AB-01096W) |
For Research Use Only | Not For Clinical Use.
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