Mouse Anti-GCH1 Antibody (CBMOAB-33899FYC)
Cat: CBMOAB-33899FYC
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-33899FYC | Monoclonal | A. thaliana (Arabidopsis thaliana), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) | WB, ELISA | MO33899FC | 100 µg | ||
| CBMOAB-43465FYA | Monoclonal | Rhesus (Macaca mulatta) | WB, ELISA | MO43465FYA | 100 µg | ||
| CBMOAB-77680FYA | Monoclonal | Zebrafish (Danio rerio) | WB, ELISA | MO77680FYA | 100 µg | ||
| MO-AB-02045Y | Monoclonal | Chicken (Gallus gallus) | WB, ELISA | MO02045Y | 100 µg | ||
| MO-AB-16160W | Monoclonal | Chimpanzee (Pan troglodytes) | WB, ELISA | MO16160W | 100 µg | ||
| MO-AB-25964H | Monoclonal | Rat (Rattus norvegicus) | WB, ELISA | MO25964C | 100 µg | ||
| MO-AB-55907W | Monoclonal | Marmoset | WB, ELISA | MO55907W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | A. thaliana (Arabidopsis thaliana), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) |
| Clone | MO33899FC |
| Specificity | This antibody binds to Arabidopsis GCH1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. (From NCBI) |
| Product Overview | Mouse Anti-Arabidopsis GCH1 Antibody is a mouse antibody against GCH1. It can be used for GCH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | GTP Cyclohydrolase 1; GTP Cyclohydrolase I; Dystonia 14; EC 3.5.4.16; GTP-CH-I; DYT5; GCH; Guanosine 5-Triphosphate Cyclohydrolase I |
| UniProt ID | Q9SFV7 |
| Protein Refseq | The length of the protein is 466 amino acids long. The sequence is show below: MGALDEGCLNLELDIGMKNGCIELAFEHQPETLAIQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDEGVGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVFAKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHIHFPSLDLDSLNLSSHRGFVKLLVSSGSGVFEDESSNLWGEFQSFLMFKGVKTQALCRNGSSVKEWCPSVKSSSKLSPEVDPEMVSAVVSILKSLGEDPLRKELIATPTRFLKWMLNFQRTNLEMKLNSFNPAKVNGEVKEKRLHCELNMPFWSMCEHHLLPFYGVVHIGYFCAEGSNPNPVGSSLMKAIVHFYGFKLQVQERMTRQIAETLSPLVGGDVIVVAEAGHTCMISRGIEKFGSSTATIAVLGRFSSDNSARAMFLDKIHTTNALKTESSSPF. |
For Research Use Only | Not For Clinical Use.
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