Mouse Anti-GCH1 Antibody (CBMOAB-33899FYC)


Cat: CBMOAB-33899FYC
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-33899FYC Monoclonal A. thaliana (Arabidopsis thaliana), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) WB, ELISA MO33899FC 100 µg
CBMOAB-43465FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO43465FYA 100 µg
CBMOAB-77680FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO77680FYA 100 µg
MO-AB-02045Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO02045Y 100 µg
MO-AB-16160W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO16160W 100 µg
MO-AB-25964H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO25964C 100 µg
MO-AB-55907W Monoclonal Marmoset WB, ELISA MO55907W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Marmoset, Rat (Rattus norvegicus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
CloneMO33899FC
SpecificityThis antibody binds to Arabidopsis GCH1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
Product OverviewMouse Anti-Arabidopsis GCH1 Antibody is a mouse antibody against GCH1. It can be used for GCH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesGTP Cyclohydrolase 1; GTP Cyclohydrolase I; Dystonia 14; EC 3.5.4.16; GTP-CH-I; DYT5; GCH; Guanosine 5-Triphosphate Cyclohydrolase I
UniProt IDQ9SFV7
Protein RefseqThe length of the protein is 466 amino acids long. The sequence is show below: MGALDEGCLNLELDIGMKNGCIELAFEHQPETLAIQDAVKLLLQGLHEDVNREGIKKTPFRVAKALREGTRGYKQKVKDYVQSALFPEAGLDEGVGQAGGVGGLVVVRDLDHYSYCESCLLPFHVKCHIGYVPSGQRVLGLSKFSRVTDVFAKRLQDPQRLADDICSALQHWVKPAGVAVVLECSHIHFPSLDLDSLNLSSHRGFVKLLVSSGSGVFEDESSNLWGEFQSFLMFKGVKTQALCRNGSSVKEWCPSVKSSSKLSPEVDPEMVSAVVSILKSLGEDPLRKELIATPTRFLKWMLNFQRTNLEMKLNSFNPAKVNGEVKEKRLHCELNMPFWSMCEHHLLPFYGVVHIGYFCAEGSNPNPVGSSLMKAIVHFYGFKLQVQERMTRQIAETLSPLVGGDVIVVAEAGHTCMISRGIEKFGSSTATIAVLGRFSSDNSARAMFLDKIHTTNALKTESSSPF.
For Research Use Only | Not For Clinical Use.
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