Mouse Anti-Arabidopsis MBD6 Antibody (CBMOAB-36276FYC)


Cat: CBMOAB-36276FYC
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityA. thaliana (Arabidopsis thaliana)
CloneMO36276FC
SpecificityThis antibody binds to Arabidopsis MBD6.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe Arabidopsis genome is predicted to encode 13 canonical MBD proteins, although only three of them, MBD5, MBD6, and MBD7, specifically bind methylated CG sites in vitro. The functions of these plant MBD proteins are poorly understood, but available information is consistent with a conserved role as DNA methylation effectors leading to transcriptional repression.
Product OverviewMouse Anti-Arabidopsis MBD6 Antibody is a mouse antibody against MBD6. It can be used for MBD6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMethyl-CpG Binding Domain Protein 6; Methyl-CpG-Binding Protein MBD6; KIAA1887
UniProt IDQ9LTJ1
Protein RefseqThe length of the protein is 225 amino acids long. The sequence is show below: MSDSVAGDFPPDPLLASGAFISSAGDGTLDSSAKRRPIQGGIGISGSGESVRIGMANGTDQVNHQTESKSRKRAAPGDNWLPPGWRVEDKIRTSGATAGSVDKYYYEPNTGRKFRSRTEVLYYLEHGTSKRGTKKAENTYFNPDHFEGQGSNRVTRTATVPPPPPPPLDFDFKNPPDKVSWSMANAGEEGWIPNIGDVKVQDSVRRDWSTAFTFITSRNPSKVSA.

Reference

ReferenceLang, Z., Lei, M., Wang, X., Tang, K., Miki, D., Zhang, H., ... & Zhu, J. K. (2015). The methyl-CpG-binding protein MBD7 facilitates active DNA demethylation to limit DNA hyper-methylation and transcriptional gene silencing. Molecular cell, 57(6), 971-983.
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For Research Use Only | Not For Clinical Use.
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