Rabbit Anti-ARNTL Antibody (MO-DKB-01056W)


Cat: MO-DKB-01056W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Pig (Sus scrofa), Bovine (Bos taurus), Chicken (Gallus gallus), Rhesus (Macaca mulatta), Sheep (Ovis aries), Frog (Xenopus)
ImmunogenRecombinant protein containing sequences in the central region of human BMAL1.
EpitopeThe epitope is in the Center of ARNTL.
FormatLiquid or Lyophilized
Buffer0.1M Tris, pH 7, 0.1M Glycine, 10% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified
Cellular LocalizationNucleus

Application Information

ApplicationWB, IF
Application NotesWestern Blot 1:500-1:3000
Immunocytochemistry/Immunofluorescence 1:100-1:1000

Target

IntroductionThe protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Product OverviewThis product is a Rabbit antibody against the Center of the ARNTL. It can be used for ARNTL detection in Western Blot, Immunofluorescence.
Alternative NamesAryl Hydrocarbon Receptor Nuclear Translocator Like; Brain And Muscle ARNT-Like 1; Class E Basic Helix-Loop-Helix Protein 5; Basic Helix-Loop-Helix Family Member E5; Basic-Helix-Loop-Helix-PAS Protein MOP3; PAS Domain-Containing Protein 3; PAS Domain Containing 3; Member Of PAS Protein 3; BHLH-PAS Protein JAP3; BHLHe5; BMAL1;
Gene ID406
UniProt IDO00327
For Research Use Only | Not For Clinical Use.
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