Mouse Anti-Frog arntl Antibody (MO-AB-01603H)


Cat: MO-AB-01603H
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO01603C
SpecificityThis antibody binds to Frog arntl.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a mouse antibody against arntl. It can be used for arntl detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesLOC503673 protein; LOC503673
UniProt IDQ6DDK7
Protein RefseqThe length of the protein is 627 amino acids long.
The sequence is show below: MADQRMDISSTMNDFMSPSSTDLISSSLGMGGIDCNRKRKGSLTDYQTDGFSFDEGMDTDKDDPHGLLDFSEGRLRNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGAANPYTEANYKPAFLSDDELKQLILRAADGFLFVVGCDRGKILFVSESVFKILNYSQNDLIGQSLFDYLHPKDIAKVKEQLSSSDTAPRERLIDAKTGLPVKTDITPGPTRLCSGARRSFFCRMKCNRPSLKVENKDFPSNCSKKKADRKSFCTIHSTGYLKSWPPTKMGLDEDNEPDNEGCNLSCLVAIGRLHPHIVPQPGNGEIRVKSTEYVSRHAVDGKFVFVDQRATAILGYLPQELLGTSCYEYFHHDDLGNLAECHRQVLQSREKITTNCFKFKIKDGSFITLKSRWFSFMNPWTKEVEYIVSTNTVVSANILDAGDSTFSHLSASPPSMDSVLQSSEGGTKRNHPAVPGIPGGTSAGAGKIGRMIADEILEFHRTRGSSPSSCGSSPLNFSTPPPDASSPGGKKMSNGGGMDPISTLVPGMDSYGFPYSDSSSIPGDSSHMDTYMTETDQGSSSPSNDEAAMAVIMSLLEADAGLGGPVDFSDLPWPL.
For Research Use Only | Not For Clinical Use.
Online Inquiry