Anti-ATG4B Antibody (Cat MO-MMB-0630), Rabbit IgG


Cat: MO-MMB-0630
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityZebrafish (Danio rerio)
ImmunogenKLH coupling synthetic peptide between 1-30 amino acids in the N-terminal region of DANRE atg4b.
EpitopeN-terminus
FormatLiquid or Lyophilized
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationWB
Application NotesWB: 1:1000
The optimal dilution should be determined by the end user.

Target

IntroductionAutophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alternative NamesAtg4b protein; atg4
UniProt IDQ6DG88
For Research Use Only | Not For Clinical Use.
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