Rabbit Anti-ATP6V1A Antibody (MO-DKB-00699W)


Cat: MO-DKB-00699W
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Specifications

Host speciesRabbit (Oryctolagus cuniculus)
Species ReactivityHuman (Homo sapiens), Mouse (Mus musculus), Rhesus (Macaca mulatta)
ImmunogenRecombinant protein containing sequences in the central region of human ATP6V1A.
EpitopeThe epitope is in the Center of ATP6V1A.
FormatLiquid or Lyophilized
BufferPBS, pH 7, 20% Glycerol
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurityAffinity purified

Application Information

ApplicationWB, IF, IHC, IHC-P, IP, KO
Application NotesWestern Blot 1:1000-1:10000
Immunocytochemistry/Immunofluorescence 1:100-1:1000
Immunohistochemistry 1:100-1:1000
Immunohistochemistry-Paraffin 1:100-1:1000
Immunoprecipitation 1:100-1:500

Target

IntroductionThis gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain A subunit isoforms and is found in all tissues. Transcript variants derived from alternative polyadenylation exist. [provided by RefSeq, Jul 2008]
Product OverviewThis product is a Rabbit antibody against the Center of the ATP6V1A. It can be used for ATP6V1A detection in Western Blot, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Knockout Validated.
Alternative NamesATPase H+ Transporting V1 Subunit A; ATPase, H+ Transporting, Lysosomal 70kDa, V1 Subunit A; Vacuolar Proton Pump Subunit Alpha; Vacuolar ATPase Isoform VA68; V-ATPase Subunit A; EC 3.6.3.14; ATP6V1A1; ATP6A1; VPP2; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump), Alpha Polypeptide, 70kD, Isoform 1; Vacuolar ATP Synthase Catalytic Subunit A, Ubiquitous Isoform; H+-Transporting ATPase Chain A, Vacuolar (VA68 Type); ATPase, H+ Transporting, Lysosomal, Subunit A1;
Gene ID523
UniProt IDP38606
For Research Use Only | Not For Clinical Use.
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