Mouse Anti-BGLAP Antibody (MOFAB-124W)


Cat: MOFAB-124W
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Specifications

Host speciesMouse
Species ReactivityHuman, Rat, Rabbit, Sheep, Goat, Chicken, Canine, Porcine
CloneWOC4
SpecificitySpecificity: γ-carboxylated residue at position 17; human, bovine, rat, rabbit, porcine, dog, goat, sheep and chicken.
ImmunogenBovine osteocalcin
FormatLiquid or Lyophilized
BufferDissolved in 10mM PBS, pH7.4, containing 1.0% BSA, and then lyophilized. The lyophilized antibody does not contain preservative.
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationPurified by column chromatography

Application Information

ApplicationWB, ELISA, IHC
Application NotesSandwich ELISA: 1-10ug/ml
IB: 1-10ug/ml
IHC: 1-10ug/ml
The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.
Product OverviewThe BGLAP antibody is used as Hormones and Serum Protein Antibodies.
Alternative NamesBone Gamma-Carboxyglutamate Protein; Gamma-Carboxyglutamic Acid-Containing Protein; Bone Gla Protein; Osteocalcin; BGP; Bone Gamma-Carboxyglutamate (Gla) Protein (Osteocalcin); Bone Gamma-Carboxyglutamate (Gla) Protein; OCN; OC
Gene ID632
UniProt IDP02818
For Research Use Only | Not For Clinical Use.
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