Rabbit Anti-Bonzo (CT) Antibody (MOFAB-160W)


Cat: MOFAB-160W
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Specifications

Host speciesRabbit
Species ReactivityMacaque, African Green Monkey
SpecificityThis antibody recognizes full-length Bonzo (40 kD).
ImmunogenPeptide corresponding to amino acids 319-338 of human Bonzo C-terminal. The sequence of this peptide is identical to that of macaque and African green monkeys.
FormatLiquid or Lyophilized
BufferPBS, pH 7.4
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationImmunoaffinity chromatography

Application Information

ApplicationWB
Application NotesIB: 1:1000
The optimal dilution should be determined by the end user.

Target

IntroductionHuman immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) require coreceptors in addition to CD4 to infect target cells. Several G protein-coupled receptors in the chemokine receptor family, including CCR5, CXCR4, CCR3, and CCR2b, have been previously identified as HIV coreceptors. An orphan G protein-coupled receptor named Bonzo was recently cloned and identified as HIV-1 and -2 and SIV coreceptor (also known as STRL33 and TYMSTR). Bonzo's messenger RNA is expressed in lymphoid tissue and activated peripheral blood lymphocytes.
Product OverviewThe Bonzo (CT) antibody is used as Infectious Disease Antibodies.
Alternative NamesBonzo; Bonzo (CT)
For Research Use Only | Not For Clinical Use.
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