Mouse Anti-Brca2 Antibody (CBMOAB-02633FYA)


Cat: CBMOAB-02633FYA
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-02633FYA Monoclonal Fruit fly (Drosophila melanogaster), Cat (Felis catus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Hamsters (Cricetinae), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Purple sea urchin (Strongylocentrotus purpuratus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio) WB, ELISA MO02633FYA 100 µg
CBMOAB-37087FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO37087FYA 100 µg
CBMOAB-67889FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO67889FYA 100 µg
MO-AB-00161L Monoclonal Elephant (Loxodonta africana) WB, ELISA MO00161L 100 µg
MO-AB-00899Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO00899Y 100 µg
MO-AB-08855W Monoclonal Cat (Felis catus) WB, ELISA MO08855W 100 µg
MO-AB-21524W Monoclonal Chimpanzee (Pan troglodytes) WB, ELISA MO21524W 100 µg
MO-AB-24185R Monoclonal Pig (Sus scrofa) WB, ELISA MO24185R 100 µg
MO-AB-29288W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO29288W 100 µg
MO-AB-30603H Monoclonal Purple sea urchin (Strongylocentrotus purpuratus) WB, ELISA MO30603C 100 µg
MO-AB-32883H Monoclonal Nile tilapia (Oreochromis niloticus) WB, ELISA MO32883C 100 µg
MO-AB-42967W Monoclonal Hamsters (Cricetinae) WB, ELISA MO42967W 100 µg
MO-AB-51934W Monoclonal Marmoset WB, ELISA MO51934W 100 µg
MO-DKB-00128W Polyclonal Zebrafish (Danio rerio) ELISA, WB 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Cat (Felis catus), Chicken (Gallus gallus), Chimpanzee (Pan troglodytes), Dog (Canis lupus familiaris), Elephant (Loxodonta africana), Hamsters (Cricetinae), Marmoset, Nile tilapia (Oreochromis niloticus), Pig (Sus scrofa), Purple sea urchin (Strongylocentrotus purpuratus), Rhesus (Macaca mulatta), Zebrafish (Danio rerio)
CloneMO02633FYA
SpecificityThis antibody binds to fruit fly Brca2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele.
Product OverviewMouse Anti-D. melanogaster Brca2 Antibody is a mouse antibody against Brca2. It can be used for Brca2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesBreast cancer type 2 susceptibility protein homolog; dmbrca2; Brca2
UniProt IDQ9W157
Protein RefseqThe length of the protein is 971 amino acids long.
The sequence is show below: MDQNGASGSHPNRLSQGRGAHARERGATVSAAANRSNIIDEMAKICEADRQTFAIARRTRGHERLAVDNSDFVAVEDLILSYAEPTPEDQVEMIMSDFCSSPTYAEDEDEPSHESEPWFRFRNKRIRTYSRKRDPKSHKAVQNEKRRGSSGLSVQRDLNTSFTSMACDFDASSQKIHEVLLNLSQYFSATATASGPTPVPSQIDLPTEARQDSGDECFNAELENLRDDLLQSGFTFEASFYENEHEQEGPGTMADTIYGDSMQSVPTTRLRLESGKRNVWSDADSTLKKADVEIAENKKLLMGQTQAKNVDIEENTNFILEGIPLSEWLTPMELPEISKDVIKHIPDKKLKLEPSSQKEQKSSKDSNASKVRGASKQSCDINTKNEGTTILDQPNAAEQENLLNDGELLEEFLFNDWQPMQCSNGPSTSKNAIQGPKENINSINLDDKEQPEKQTPNKSQTISSHQLNGIRKKSFKFIEVSEEMKIKGEEFVDKVVSGLYHFSHKCNLRTEEYSDNHSQVMESTQCAEFKSAPSKPIEILDGKETYNAIAKVDVGEINGKFSPLNNDTIAEPEFCGFRTASNKAIPISEKMKIKTAEFMAEFQSKETIQQNDYLVHQPNDKPTSVGLDTALKRSIESSEEMRSKASKLVVVDTTMREPHQPTLDPVCRDLNESQFFGFRTASNKAIEITEAMEKRGAMFLAQSKATDQLNGWQPSDFPDVLPTSPNNEIHSINVENNKAVNTKTVSETEFFGFRTASNKGIVISENTKIKVAQFMSEFQAADASTDSNQPTVISEESRNIDAKFVDEAAAEDSANKPTFCNVQSLKNTSDIEHFKHDFFVEHSAKEEHPLCSQPLVRTPRRSQEIHSSLSQLAGKSPLDQATKKSVIARRNLLSLKRKRKIILSTETSTSCALPTMERFAPKPSSTSTPLADRDLNRSKDCTKNRQDAEDMSPICMQPKKSRRLGLSRSRY.
For Research Use Only | Not For Clinical Use.
Online Inquiry