Mouse Anti-C. difficile Toxin A Antibody (MOFAB-139W)


Cat: MOFAB-139W
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Specifications

Host speciesMouse
Species ReactivityClostridium difficile
CloneWPCG4
SpecificitySpecificity: This antibody recognizes C. difficile toxin A. It does not cross-react with toxin B.
ImmunogenToxin A was purified from the culture filtrate of C. difficile 10463 and inactivated with 0.4% formalin.
FormatLiquid or Lyophilized
BufferPBS, pH 7.2
Regulatory StatusFor Research Use Only
ShippingGel Pack
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationProtein G

Application Information

ApplicationELISA, WB, IF
Application NotesELISA: 1-10ug/ml
IB: 0.5-2ug/ml
IF: 1-5ug/ml
The optimal dilution should be determined by the end user.

Target

IntroductionClostridium difficile, a Gram-positive anaerobic bacterium, is a major causative agent of colitis and diarrhea, mainly in hospitalized patients receiving antibiotics. Pathogenic C. difficile strains produce a variety of toxins. The most characterized are toxin A and toxin B, both of which may produce diarrhea and inflammation in infected patients. Toxins A and B are glucosyltransferases that target and inactivate the Rho family of GTPases. Clostridium difficile most commonly affects older adults in hospitals or long-term care facilities. However, studies have shown that C. difficile infection rates are rising in populations not traditionally considered high risk, such as young healthy individuals with no history of antibiotic use or exposure to healthcare facilities.
Product OverviewThe C. difficile Toxin A antibody is used as Infectious Disease Antibodies.
Alternative NamesClostridium difficile Toxin A; C. difficile Toxin A; Clostridium difficile Toxin A; Clostridium difficile Toxin A
Gene ID144926
For Research Use Only | Not For Clinical Use.
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