Mouse Anti-C. elegans cav-1 Antibody (Full length)


Cat: MO-NAB-00531W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneNW0453
SpecificityThis antibody is binds to C. elegans cav-1.
ImmunogenRecombinant His6-tagged CAV-1 fusion protein.
EpitopeThe epitope is in the Full length of cav-1
FormatLiquid or Lyophilized
BufferSupernatant
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIF, WB

Target

IntroductionThe scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Product OverviewThis product is a Mouse antibody against the Full length of the cav-1. It can be used for cav-1 detection in Immunofluorescence, Western Blot.
Alternative NamesCaveolin-1; cav-1
Gene ID177815
UniProt IDQ94051
See other products for " CAV-1 "
MOFY-0522-FY213Mouse Anti-CAV-1 Antibody (MOFY-0522-FY213)
For Research Use Only | Not For Clinical Use.
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