Mouse Anti-C. elegans CED2 (clone MO01253HB) Antibody (CBMOAB-01253HCB)


Cat: CBMOAB-01253HCB
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO01253HB
SpecificityThis antibody binds to C. elegans CED2.
FormatLyophilized
StorageStore at 4°C: short-term (1-2 weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma Membrane

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionRequired for cell migration and engulfment of cell corpses but not for programmed cell death/apoptosis (PubMed:10707082, PubMed:6857247, PubMed:1936965, PubMed:11449278, PubMed:15744306, PubMed:19402756, PubMed:20226672). Has a role in the migration of the 2 gonadal distal tip cells (DTCs) (PubMed:10707082). Plays a role in protecting dopaminergic neurons from oxidative stress-induced degeneration (PubMed:29346382).
Product OverviewMouse Anti-C. elegans CED2 (clone MO01253HB) Antibody (CBMOAB-01253HCB) is a mouse antibody against CED2. It can be used for CED2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCell death abnormality protein 2; Cell-corpse engulfment protein CED-2; ced-2
UniProt IDQ9NHC3
Protein RefseqThe length of the protein is 279 amino acids long. The sequence is show below: MTTNGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSSRPGEYSLTVREADEGNAVCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFKMRVLTEASLLAAYKKPIIEVVVGTFKFTGERETDLPFEQGERLEILSKTNQDWWEARNALGTTGLVPANYVQIQMEFHNDRTSKGASQSSIGSSGGGAERFSSASTSSDNIELQPRLPAKAKVTFDRVPNAYDPTQLRVKKGQTVLVTQKMSNGMYKAELDGQIGSVPHTYLRFTAVSE.
For Research Use Only | Not For Clinical Use.

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