AibGenesis™ Mouse Anti-C. elegans GAR2 Antibody (CBMOAB-04268HCB)


Cat: CBMOAB-04268HCB

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  • Specifications
  • Application Information
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneMO04268HB
SpecificityThis antibody binds to C. elegans GAR2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins (PubMed:11032868, PubMed:11700045). Primary transducing effect is Pi turnover. Regulates the activity of ventral cord motor neurons (PubMed:18614679). Couples to the G(o) alpha G-protein subunit goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of the neurotransmitter acetylcholine in ventral cord motor neurons (PubMed:18614679). As acetylcholine depolarizes body wall muscles, modulation of acetylcholine levels most likely results in the control locomotory behavior and egg-laying (PubMed:12954868, PubMed:18614679). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-C. elegans GAR2 Antibody is a mouse antibody against GAR2. It can be used for GAR2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein GAR-2, isoform c; gar-2
UniProt IDQ8MQ41
Protein RefseqThe length of the protein is 667 amino acids long. The sequence is show below: MAVASVLLALFMLFLSIVTVIGNLAVLLSYYLDKNIRQPTNYFIFSLAISDLLIGLEGIPVYTAFYLNNNEWIWGDVLCDLWLSIDYIVCLASIYTVLGITVDRYYSVKKPATYRNWRTPGRVVLIIIFIWLVPSILFSVSIFGYGTFTGTGRILKETECYVQFMTNPYLNMGMYISYYWTTLFVMLYLYWGIYRAAKKLALKSDQKTKRLALLTEMRRPEVSVRTSDAGNSSSDSPNDTSNSSKCFRTAPPTTTVQTTQTNVGTPPPVFRNHMTLHNNNMDFTKDNEIVRPPTPPDDNTYSNPNFSMISEQLTNGFSRQEPSSVIERESTAPCVSPEPSHASLENEFNENHHAHFKPELSLPFIDADSVSSMVGHDDLRRAMSIRISRSVSMQGTARATPVIEIVENLEEALKICENLEELREDENKNEEEKQKNGLENGGMNHVIIANDEQQPSTSKESEQKEEMTPENHDPNEVKVPLIAVSRVESVKSTAGGKVRRLITQMRSHSIRSKRKANKNKVSTCSPKSTTSLLLPPSTSSTTRERTRHPVTITLQFQSVLSALNFFQRKKVTREYKSRSENRARKALRTITFILGSFIILWTPFYVLATIYGFCETCKASPSFNTLYTISYYLCYMNSPLNPFCYAMANQQFKKTLTRIFKGDFRRV.
For Research Use Only | Not For Clinical Use.
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