AibGenesis™ Mouse Anti-C. elegans orc-2 Antibody (Full length)


Cat: MO-NAB-00584W

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  • Specifications
  • Application Information
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans)
CloneNW0506
SpecificityThis antibody is binds to C. elegans orc-2.
ImmunogenRecombinant His6-tagged ORC-2 fusion protein.
EpitopeThe epitope is in the Full length of orc-2
FormatLiquid or Lyophilized
BufferSupernatant
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIF, WB

Target

IntroductionThe origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate. (From NCBI)
Product OverviewThis product is a Mouse antibody against the Full length of the orc-2. It can be used for orc-2 detection in Immunofluorescence, Western Blot.
Alternative NamesOrigin recognition complex subunit 2; CeOrc2; orc-2
Gene ID174676
UniProt IDQ21037
For Research Use Only | Not For Clinical Use.
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