Mouse Anti-C. elegans PGL1 Antibody (CBMOAB-08332HCB)
Cat: CBMOAB-08332HCB
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
| Size: | |
| Conjugate: | |
| Inquiry |
- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | C. elegans (Caenorhabditis elegans) |
| Clone | MO08332HB |
| Specificity | This antibody binds to C. elegans PGL1. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Guanyl-specific endoribonuclease which cleaves the phosphodiester bond in single-stranded RNA between the 3''-guanylic residue and the 5''-OH residue of adjacent nucleotide, resulting in the formation of a corresponding 2'',3''-cyclic phosphate intermediate (PubMed:26787882). Together with the P-granule component pgl-3, is involved in the formation of P-granules (PubMed:21402787, PubMed:24746798). Together with pgl-3, probably recruits other granule components such as pos-1, mex-3 and glh-1 to P-granules (PubMed:21402787). In addition, may act redundantly with pgl-3 to protect germ cells from excessive germline apoptosis during normal oogenesis and development of the two gonadal arms (PubMed:26598553). This may in part be through regulating the localization of sir-2.1 which is involved in germ cell apoptosis (PubMed:26598553). May protect somatic cells from excessive apoptosis during normal development (PubMed:27650246). Essential role in male and female postembryonic germline development; maternally provided protein maintains a population of proliferating germ cells and zygotic expression is required for correct oogenesis (PubMed:9741628, PubMed:15238518, PubMed:24746798). |
| Product Overview | Mouse Anti-C. elegans PGL1 Antibody is a mouse antibody against PGL1. It can be used for PGL1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Protein PGL-1, isoform b; pgl-1 |
| UniProt ID | Q304E5 |
| Protein Refseq | The length of the protein is 771 amino acids long. The sequence is show below: MEVSDLRVSKRTTRRERGSCNFDLVPIFFSVFLLFWFHPFHMEANKREIVDFGGLRSYFFPNLAHYITKNDEELFNNTSQANKLAAFVLGASKDAPGDEDILEMILPNDANAAVIAAGMDVCLLLGDKFRPKFDAAAEKLSGLGHAHDLVSVIDDDKKLGMLARKAKLKKTEDAKILQALLKVIAIDDAAEKFVELTELVSQLDLDFDVYVLTKILGLISEETSDEVDIIRDNVVNAFDSCKPLLKQLMLDGPKSEPADPFISLLMDPLEESVGKVVNHIAQLFEEASKNEGDESLVLRSQLGYQLFFLIVRSLADGKREVSKKILSGIPTSVRAEVFPGLQRSVYKSAVFLGNHIIQVLLGSKKSFEDWDVVGVAKDLESAWKRRAIAELIKKFQVSILEQCFDKPVPLIPQSPLNNDAVIDNVNKALQFALWLTEFYGSENETEALGELRFLDSTSKNLLVDSFKKFVQGINSKTHVTRIVESLEKCCLSDTPSGRKSNVQPSTSQQQDSAYTKEEMTTVHNTYSVNTKAQVLNGLSDTNSSGLLVDSKDSLSLQEISCDEVDSSTLLSSSRNIGEGVTVKAVDPVPEKVNDAQQQQTVNEIEMASDANQDTSSSASPEVAPSFSTDGWDSPTKSVALPPGMQQIDEEETTVADKDSTPQPQARAETAWGSGDATPMPLPAPTNQYKVSGFGEAKVAKGFGQFAPTSSAYGGGGGRGGYGGGDRGGRGGYGGDRGGRGGYGGGDRGGRGGYGGDRGRGGYGGRGGRGGF. |
For Research Use Only | Not For Clinical Use.
Online Inquiry