Mouse Anti-C. elegans Rad51 Antibody (MO-NAB-00073W)


Cat: MO-NAB-00073W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Chicken (Gallus gallus)
CloneNW0112
SpecificityRad51, a 37 kDa protein, is the human homolog of E. coli RecA protein and a member of the RAD52 epistasis group in S. cerevisiae.
FormatLiquid or Lyophilized
BufferPBS
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
PurificationAntigen Affinity-purified

Application Information

ApplicationWB, ChIP, IF, IHC, IHC-Fr, IHC-P, In vitro, IP, PLA, KD
Application NotesWB: 1/100-1/3000
IF: 1/100-1/1000
IHC-P: 1/100-1/1000

Target

IntroductionThe protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Product OverviewMouse Anti-C. elegans Rad51 (clone NW0112) Antibody (MO-NAB-00073W) is a Mouse antibody against the epitope of the Rad51. It can be used for Rad51 detection in Western Blot, Chromatin Immunoprecipitation, Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, In vitro, Immunoprecipitation, PLA, KD.
Alternative NamesRAD51 Recombinase; BRCA1/BRCA2-Containing Complex, Subunit 5; RAD51 Homolog A; HsRad51; HRAD51; RAD51A; RECA; RAD51 Homolog (RecA Homolog, E. Coli) (S. Cerevisiae); RAD51 (S. Cerevisiae) Homolog (E Coli RecA Homolog); DNA Repair Protein RAD51 Homolog 1
Gene ID5888
UniProt IDQ06609
For Research Use Only | Not For Clinical Use.
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