Mouse Anti-Cattle FEN1 Antibody (MO-AB-12487R)
Cat: MO-AB-12487R
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Size: | |
Conjugate: | |
Inquiry |
- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO12487R |
Specificity | This antibody binds to Cattle FEN1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Mitochondrion; Nucleus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | Structure-specific nuclease with 5''-flap endonuclease and 5''-3'' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5''-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5''-end of a downstream Okazaki fragment. It enters the flap from the 5''-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5''-3'' exonuclease activity on nicked or gapped double-stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA. |
Product Overview | Mouse Anti-Cattle FEN1 Antibody is a mouse antibody against FEN1. It can be used for FEN1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Flap endonuclease 1; FEN-1; EC 3.1.-.-; Flap structure-specific endonuclease 1; FEN1; RTH-1 |
UniProt ID | Q58DH8 |
Protein Refseq | The length of the protein is 380 amino acids long. The sequence is show below: MGIQGLAKLIADVAPSAIRENDIKSYFGRKVAIDASMSIYQFLIAVRQGGDVLQNEEGETTSHLMGMFYRTIRMMENGIKPVYVFDGKPPQLKSGELAKRSERRAEAEKQLQEAQAAGAEAEVEKFTKRLVKVTKQHNDECKHLLSLMGIPYLDAPSEAEASCAALVKAGKVYAAATEDMDCLTFGSPVLMRHLTASEAKKLPIQEFHLSRILQELGLNQEQFVDLCILLGSDYCESIRGIGPKRAVDLIQKHKS. |
See other products for " FEN1 "
MO-DKB-00056W | Rabbit Anti-FEN1 Antibody (MO-DKB-00056W) |
MO-AB-27568W | Mouse Anti-Cottonwood FEN1 Antibody (MO-AB-27568W) |
MO-AB-43140W | Mouse Anti-Hamsters FEN1 Antibody (MO-AB-43140W) |
MO-AB-55387W | Mouse Anti-Marmoset FEN1 Antibody (MO-AB-55387W) |
CBMOAB-16738FYA | Mouse Anti-D. melanogaster Fen1 Antibody (CBMOAB-16738FYA) |
MO-AB-08061Y | Mouse Anti-Rabbit FEN1 Antibody (MO-AB-08061Y) |
MO-AB-00479R | Mouse Anti-Medaka FEN1 Antibody (MO-AB-00479R) |
MO-AB-15236Y | Mouse Anti-Sheep FEN1 Antibody (MO-AB-15236Y) |
MO-AB-44725W | Mouse Anti-Horse FEN1 Antibody (MO-AB-44725W) |
MO-DKB-00054W | Rabbit Anti-FEN1 Antibody (MO-DKB-00054W) |
For Research Use Only | Not For Clinical Use.
Online Inquiry