Mouse Anti-Cattle FUT3 Antibody (MO-AB-12762R)
Cat: MO-AB-12762R
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Cattle (Bos taurus) |
Clone | MO12762R |
Specificity | This antibody binds to Cattle FUT3. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Golgi apparatus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. |
Product Overview | Mouse Anti-Cattle FUT3 Antibody is a mouse antibody against FUT3. It can be used for FUT3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Galactoside 3(4)-L-fucosyltransferase; EC 2.4.1.65; Blood group Lewis alpha-4-fucosyltransferase; Lewis FT; FUTB; Fucosyltransferase 3; Fucosyltransferase III; FucT-III; FUT3 |
UniProt ID | Q11126 |
Protein Refseq | The length of the protein is 365 amino acids long. The sequence is show below: MYPPGCAKVKCSWHHCLPGLLLQLLLALCFFSYLRMSQEKPKPKPMWVSELGAPSQATEGSSAHLPLRVLLWTWPFNQPVALSRCSELWPGTADCQLTVNRSEYPQADAVLVHHREVSHRPQMQLPPSPRPPGQRWVWFSMESPSNCLKLKDLDGYFNLTMSYRRDSDIFMPYGWLEPWPSQPVETLLNISAKTKLVAWVVSNWNTDSIRVQYYKLLKPHLQVDVYGRFHTPLPHALMAKQLSQYKFYLAFENSL. |
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For Research Use Only | Not For Clinical Use.
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