Mouse Anti-Frog fut3 Antibody (MO-AB-03733H)


Cat: MO-AB-03733H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO03733C
SpecificityThis antibody binds to Frog fut3.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationGolgi apparatus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
Product OverviewThis product is a mouse antibody against fut3. It can be used for fut3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAlpha 1,3/4 fucosyltransferase Lewis 2; fut3
UniProt IDQ6WNG3
Protein RefseqThe length of the protein is 347 amino acids long.
The sequence is show below: MESNKWKKRFFFCFVQCIFSIMFFILFGSKGNSTEKIPQRSELTFRPESSQLTILLWTWPFNYHFPLNDCPTDLDSSGCFFTVNRSLYPSANAVIIHHREVYKNKSILPQIPRPTNQYWIWFNKESRSHSPNLHIMENLINLTMSFRADSDIFTPYGRLERNDGSQNFTIPVKSKLVAWVISNWNKNSKRYKYYSKLKKHLNIDVYGSKTKVLSHTNTLETLSQYKFYLAFENSIHEDYITEKLWSNSLLSGTVPVVLGPSRKNYERFIPSDSFIHVEDFSTPQKLALYLLELDKNDERYRQYFNWRSRLQPMKNRIDCVSDYCRVCKVLKEAPPYKTIPSIDTWFR.
For Research Use Only | Not For Clinical Use.
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