Mouse Anti-Cattle MLC1 Antibody (MO-AB-15831R)


Cat: MO-AB-15831R
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
CloneMO15831R
SpecificityThis antibody binds to Cattle MLC1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Lysosome; Endosome; Endoplasmic reticulum; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionEssential light chain for the class II conventional myosin MYO1. Acts also as light chain for the class V unconventional myosin MYO2 and for IQG1. Involved in the assembly of the contractile actomyosin ring at the bud neck during cytokinesis by recruiting IQG1 to the bud neck. Also required for chitin and MYO2-dependent secretory vesicle deposition to the center of the bud neck for septum formation. May stabilize MYO2 by binding to its IQ domains. Its major function is probably not to regulate MYO1 activity, but rather to coordinate actin ring formation and targeted membrane deposition during cytokinesis via its interactions with MYO1, IQG1 and MYO2.
Product OverviewMouse Anti-Cattle MLC1 Antibody is a mouse antibody against MLC1. It can be used for MLC1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMegalencephalic leukoencephalopathy with subcortical cysts 1; MLC1
UniProt IDQ08E21
Protein RefseqThe length of the protein is 378 amino acids long.
The sequence is show below: MAREEQCREGLAYDRMPPLERGRPDAAGYALDTKPGDLQLSSRLPPCFSRKTWVFSVLMGGCLLVTSGFSLYLGNVFPLEMDYLRCAAGSCIPSAIVSFAVSRRNVSAIPHFQILFVSTFAVTTSCLIWFGCKLVLNPSAVDINFNLILLLLLELFMAATVIISARSSEAPCKQKGSISESSSVLYEVTFPARVLKSYSVIEVVAGVSAILGGVIALNVDDTVSGPHFSVTFFWVLVACFPSAIASHVTAECPSR.
For Research Use Only | Not For Clinical Use.
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