Mouse Anti-Cattle PTPRC Antibody (MO-AB-18836R)

Cat: MO-AB-18836R
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  • Product Details


Host speciesMouse (Mus musculus)
Species ReactivityCattle (Bos taurus)
SpecificityThis antibody binds to Cattle PTPRC.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.


IntroductionProtein tyrosine phosphatase, receptor type, C, also known as PTPRC, is an enzyme encoded by the PTPRC gene in humans. PTPRC is also called CD45 antigen (CD stands for differentiation cluster) and was originally called Leukocyte Common Antigen (LCA).

The protein product of this gene, most famously CD45, is a member of the protein tyrosine phosphatase (PTP) family. PTP is a signaling molecule that regulates various cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation.

CD45 is a type I transmembrane protein and exists in various isoforms in all differentiated hematopoietic cells (except red blood cells and plasma cells). CD45 has been shown to be an important regulator of T cell and B cell antigen receptor signal transduction. It plays a role by directly interacting with the components of the antigen receptor complex through its extracellular domain (a form of co-stimulation), or through its cytoplasmic domain to activate various Src family kinases required for antigen receptor signal transduction. CD45 can also inhibit JAK kinase, so it can be used as a negative regulator of cytokine receptor signal transduction.
Product OverviewThis product is a mouse antibody against PTPRC. It can be used for PTPRC detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesPTPRC protein, Fragment; PTPRC
UniProt IDA6QNL1
Protein RefseqThe length of the protein is 806 amino acids long.
For Research Use Only | Not For Clinical Use.
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