Mouse Anti-CD5 Antibody (MO-AB-09869R)

Cat: MO-AB-09869R

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Product List
Specifications
Application Information
Target
Reference
Relate Reference Data

Sub Cat	Clonality	Species Reactivity	Application	Clone	Conjugate	Size
MO-AB-09869R	Monoclonal	Cattle (Bos taurus), Alpaca (Vicugna pacos), Llama (camel), Dog (Canis lupus familiaris), Feline, Lion, Goat (Capra hircus), Human, Rhesus, Cynomolgus, Chimpanzee, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries)	WB, ELISA	MO09869R		100 µg	Inquiry
Protein Refseq: The length of the protein is 495 amino acids long. The sequence is show below: MGSQHLPLAALYLLELLVTSCLGGLKVEVQGLTMRLSGSGSRCQGRLEVSNGTEWYAVHSQSWGQLSLYQVAPRQFLKLCQELQCRDPLLLSSSRYFKEVQFQKLIICHGQLGSFSNCSLNRGRQVDSLALICLEPPRTTAPPTTSPPTTTPEPTAPPRFQLVAEPGGLRCAGVVEFYSGGLGGTIGIEPQNDIKDLGQLICAALQCGSFLKPLPETEEAQTQKPEGQRPLPIRWEIQNPKCTSLEQCFRKVQPW.
CBMOAB-00040FYA	Monoclonal	Cattle (Bos taurus)	FC	F00040FYA		100 µg	Inquiry
CBMOAB-00041FYA	Monoclonal	Cattle (Bos taurus)	FC	F00041FYA		100 µg	Inquiry
CBMOAB-00042FYA	Monoclonal	Cattle (Bos taurus)	FC	F00042FYA		100 µg	Inquiry
CBMOAB-00134FYA	Monoclonal	Dog (Canis lupus familiaris)	FC	F00134FYA		100 µg	Inquiry
CBMOAB-00140FYA	Monoclonal	Goat (Capra hircus)	FC	F00140FYA		100 µg	Inquiry
CBMOAB-00179FYA	Monoclonal	Rabbit (Oryctolagus cuniculus)	FC	F00179FYA		100 µg	Inquiry
CBMOAB-00198FYA	Monoclonal	Pig (Sus scrofa)	FC	F00198FYA		100 µg	Inquiry
CBMOAB-00219FYA	Monoclonal	Alpaca (Vicugna pacos), Llama (camel)	FC	F00219FYA		100 µg	Inquiry
MO-AB-14505Y	Monoclonal	Sheep (Ovis aries)	WB, ELISA	MO14505Y		100 µg	Inquiry
Protein Refseq: The length of the protein is 442 amino acids long. The sequence is show below: EWYAVHGQSWGQSSLYQVMPKQFFKLCQKLQCRDPLLLSSLHHFKDRPFQKLMICHGQLGSFSNCSLNRGHQVGPLALICSEPPRTTAPPTTSPPTTTPEPTAPPRFQLVAEPGGLRCAGLVEFYSGGVGGTIGIEPQDEIKDLGQLICAALQCGSFLKPLPETEEAQTPKPGGQRPLPIRWEIQNPRCNSLEQCFRKVQPRAGGQALGLICSDFQPKVQSRLVGGSDMCEGSVEVRSGKGQQWDTLCDSSWAKGTARWEEVCREQQCGNVSFYQGLDPSEKTLGGLYCPSGILSQCHKLEEKKSYCKRVFVTCQNSSRAGLGVGAVMSIILALVLLAVLLVVCGPLAYKKVVKKFRQKKQRQWIGPTGMNQNMSFHRNHTVTVWSQAENATASHVENEYSQPPRNSQISAYPALEGALHRISTHPDNSSDSDYELHGAQRL.
MOFY-0522-FY49	Monoclonal	Human, Rhesus, Cynomolgus, Chimpanzee	FC, IHC, WB, IP			100 µg	Inquiry
MOFY-0522-FY69	Monoclonal	Feline, Lion	FC, IHC			100 µg	Inquiry

Specifications

Host species	Mouse (Mus musculus)
Species Reactivity	Cattle (Bos taurus), Alpaca (Vicugna pacos), Llama (camel), Dog (Canis lupus familiaris), Feline, Lion, Goat (Capra hircus), Human, Rhesus, Cynomolgus, Chimpanzee, Pig (Sus scrofa), Rabbit (Oryctolagus cuniculus), Sheep (Ovis aries)
Clone	MO09869R
Specificity	This antibody binds to Cattle CD5.
Format	Liquid or Lyophilized
Storage	Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use
Purity	> 90% was determined by SDS-PAGE
Purification	Purified with Protein A or G affinity chromatography
Cellular Localization	Plasma membrane; Other locations

Application Information

Application	WB, ELISA
Application Notes	ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

Introduction	As with human CD5+ B cells, we report here that CD5 is physically associated with the B cell receptor (BCR) in normal bovine CD5+ B cells. In contrast, in CD5+ B cells from BLV-infected PL cattle, CD5 was dissociated from the BCR. In B cells from PL cattle, apoptosis was reduced when cells were stimulated with surface immunoglobulin M (sIgM) antibodies, whereas in B cells from uninfected cattle, apoptosis was increased after sIgM stimulation.
Product Overview	Mouse Anti-Cattle CD5 Antibody is a mouse antibody against CD5. It can be used for CD5 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative Names	T-cell surface glycoprotein CD5; CD antigen CD5; CD5
UniProt ID	P19238
Protein Refseq	The length of the protein is 495 amino acids long. The sequence is show below: MGSQHLPLAALYLLELLVTSCLGGLKVEVQGLTMRLSGSGSRCQGRLEVSNGTEWYAVHSQSWGQLSLYQVAPRQFLKLCQELQCRDPLLLSSSRYFKEVQFQKLIICHGQLGSFSNCSLNRGRQVDSLALICLEPPRTTAPPTTSPPTTTPEPTAPPRFQLVAEPGGLRCAGVVEFYSGGLGGTIGIEPQNDIKDLGQLICAALQCGSFLKPLPETEEAQTQKPEGQRPLPIRWEIQNPKCTSLEQCFRKVQPW.

Reference

1. Cantor, G. H., Pritchard, S. M., Dequiedt, F., Willems, L., Kettmann, R., & Davis, W. C. (2001). CD5 is dissociated from the B-cell receptor in B cells from bovine leukemia virus-infected, persistently lymphocytotic cattle: consequences to B-cell receptor-mediated apoptosis. Journal of Virology, 75(4), 1689-1696.
2. Stabel, J. R., & Khalifeh, M. S. (2008). Differential expression of CD5 on B lymphocytes in cattle infected with Mycobacterium avium subsp. paratuberculosis. Veterinary immunology and immunopathology, 126(3-4), 211-219.
3. Morrison, W. I., Howard, C. J., & Hinson, C. A. (1991). Polymorphism of the CD4 and CD5 differentiation antigens in cattle. Veterinary immunology and immunopathology, 27(1-3), 235-238.

See other products for " CD5 "

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CBMOAB-00133FYA	Mouse Anti-CD5 Antibody (CBMOAB-00133FYA)
CBMOAB-38725FYA	Mouse Anti-CD5 Antibody (CBMOAB-38725FYA)
MO-AB-01065Y	Mouse Anti-CD5 Antibody (MO-AB-01065Y)
CBMOAB-00168FYA	Mouse Anti-CD5 Antibody (CBMOAB-00168FYA)
CBMOAB-00148FYA	Mouse Anti-CD5 Antibody (CBMOAB-00148FYA)

Relate Reference Data

Figure 1 CD5 coimmunoprecipitates with the BCR in uninfected animals. B cells were enriched from PBMCs by T-cell depletion. Lanes 1 to 3, biotin-labeled cells in 1% digitonin lysis buffer were immunoprecipitated (IP) with either MAb to CD79a (the Ig-alpha component of the BCR) or isotype control MAb AV64A. Precipitates were resuspended in 1% NP-40 lysis buffer, and a second immunoprecipitation was performed using MAb to CD5 (MUCIA) or isotype control MAb. As a control, CD5 was immunoprecipitated directly from the PBMC NP-40 lysate using MAb to CD5 (lane 4).

For Research Use Only | Not For Clinical Use.

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