Mouse Anti-cd8a Antibody (CBMOAB-69724FYA)


Cat: CBMOAB-69724FYA
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Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-69724FYA Monoclonal Zebrafish (Danio rerio), Alpaca (Vicugna pacos), Llama (camel), Bison (Bison bison), Cattle (Bos taurus), Goat (Capra hircus), Sheep (Ovis aries), Water buffalo (Bubalus bubalis), Cat (Felis catus), Chicken, Chicken (Gallus gallus), Turkey, Guinea, Dog (Canis lupus familiaris), Deer, Elk (Cervus elaphus), Guinea pig (Cavia porcellus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Mouse (Mus musculus), Pig (Sus scrofa), Porcine, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta) WB, ELISA MO69724FYA 100 µg
CBMOAB-00078FYA Monoclonal Bison (Bison bison), Cattle (Bos taurus), Goat (Capra hircus), Sheep (Ovis aries), Water buffalo (Bubalus bubalis) FC 7C2B 100 µg
CBMOAB-00081FYA Monoclonal Cattle (Bos taurus) FC F00081FYA 100 µg
CBMOAB-00082FYA Monoclonal Bison (Bison bison), Cattle (Bos taurus), Goat (Capra hircus), Sheep (Ovis aries), Water buffalo (Bubalus bubalis) FC F00082FYA 100 µg
CBMOAB-00083FYA Monoclonal Bison (Bison bison), Cattle (Bos taurus), Goat (Capra hircus), Sheep (Ovis aries), Water buffalo (Bubalus bubalis) FC F00083FYA 100 µg
CBMOAB-00132FYA Monoclonal Dog (Canis lupus familiaris) FC F00132FYA 100 µg
CBMOAB-00144FYA Monoclonal Horse (Equus caballus) FC F00144FYA 100 µg
CBMOAB-00146FYA Monoclonal Horse (Equus caballus) FC F00146FYA 100 µg
CBMOAB-00169FYA Monoclonal Goat (Capra hircus), Deer, Elk (Cervus elaphus), Sheep (Ovis aries) FC F00169FYA 100 µg
CBMOAB-00174FYA Monoclonal Rabbit (Oryctolagus cuniculus) FC F00174FYA 100 µg
CBMOAB-00175FYA Monoclonal Rabbit (Oryctolagus cuniculus) FC F00175FYA 100 µg
CBMOAB-00195FYA Monoclonal Pig (Sus scrofa) FC F00195FYA 100 µg
CBMOAB-00197FYA Monoclonal Pig (Sus scrofa) FC F00197FYA 100 µg
CBMOAB-00220FYA Monoclonal Alpaca (Vicugna pacos), Llama (camel) FC F00220FYA 100 µg
CBMOAB-38745FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO38745FYA 100 µg
MO-AB-08086W Monoclonal Cat (Felis catus) WB, ELISA MO08086W 100 µg
MO-AB-29492W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO29492W 100 µg
MO-AB-41379W Monoclonal Guinea pig (Cavia porcellus) WB, ELISA MO41379W 100 µg
MO-AB-52590W Monoclonal Marmoset WB, ELISA MO52590W 100 µg
MO-AB-09889R Monoclonal Cattle (Bos taurus) WB, ELISA MO09889R 100 µg
MO-AB-23028H Monoclonal Mallard (Anas platyrhynchos) WB, ELISA MO23028C 100 µg
MO-AB-24659H Monoclonal Rat (Rattus norvegicus) WB, ELISA MO24659C 100 µg
MO-AB-01078Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO01078Y 100 µg
MO-NAB-00316W Monoclonal Mouse (Mus musculus) ELISA, IF, FC NW0244 100 µg
MO-NAB-00317W Monoclonal Mouse (Mus musculus) ELISA, FC NW0245 100 µg
MOFY-0522-FY4 Monoclonal Chicken, Turkey, Guinea FC, IHC, IP, BL 100 µg
MOFY-0522-FY10 Monoclonal Chicken FC 100 µg
MOFY-0522-FY24 Monoclonal Chicken, Turkey FC, IHC, WB, IP 100 µg
MOFY-0522-FY53 Monoclonal Porcine FC, IHC 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityZebrafish (Danio rerio), Alpaca (Vicugna pacos), Llama (camel), Bison (Bison bison), Cattle (Bos taurus), Goat (Capra hircus), Sheep (Ovis aries), Water buffalo (Bubalus bubalis), Cat (Felis catus), Chicken, Chicken (Gallus gallus), Turkey, Guinea, Dog (Canis lupus familiaris), Deer, Elk (Cervus elaphus), Guinea pig (Cavia porcellus), Horse (Equus caballus), Mallard (Anas platyrhynchos), Marmoset, Mouse (Mus musculus), Pig (Sus scrofa), Porcine, Rabbit (Oryctolagus cuniculus), Rat (Rattus norvegicus), Rhesus (Macaca mulatta)
CloneMO69724FYA
SpecificityThis antibody binds to Zebrafish cd8a.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD8A (CD8a Molecule) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Primary Cutaneous Aggressive Epidermotropic Cd8+ T-Cell Lymphoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and T-Cell Receptor and Co-stimulatory Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity.
Product OverviewMouse Anti-Zebrafish cd8a Antibody is a mouse antibody against cd8a. It can be used for cd8a detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCD8 alpha; cd8a; CD8 alph
UniProt IDQ5H7M0
Protein RefseqThe length of the protein is 216 amino acids long.
The sequence is show below: MYQISTGFCVILSLFYGCSANFHQENSTVAVNCNPKTSGTITFMFQINSTGANCLLIAKQTEVKHNANSKKYSGHIDSNGNLNVKIKSFAKRTDSGLYVCATMNNNKLFFGEVTKIQGVPDPVTQGPKMIQTTLKPVVKTTMIKQCVCDKKGAKPMFKCETWIFTSLVGGCGLFLVLLIATIVYCNRLRTRRCPHHYKRQPRGPPAGHAKMPNSHF.

Reference

Reference1. Kasheta, M., Painter, C. A., Moore, F. E., Lobbardi, R., Bryll, A., Freiman, E., ... & Ceol, C. J. (2017). 1. Identification and characterization of T reg-like cells in zebrafish. Journal of Experimental Medicine, 214(12), 3519-3530.
2. Miyazawa, R., Matsuura, Y., Shibasaki, Y., Imamura, S., & Nakanishi, T. (2018). Cross-reactivity of monoclonal antibodies against CD4-1 and CD8α of ginbuna crucian carp with lymphocytes of zebrafish and other cyprinid species. Developmental & Comparative Immunology, 80, 15-23.
3. Ding, C., Fan, E., Wang, S., Guo, L., Li, J., & Liu, Q. (2017). A potential aquaculture vaccine vector: evaluation of a double-gene attenuated Listeria monocytogenes in zebrafish (Danio rerio). Aquaculture, 479, 311-320.

Relate Reference Data

Figure 1 qRT-PCR of selected genes in foxp3a:EGFP-positive thymocytes relative to bulk thymocytes. Relative CD4 and CD8 expression is also shown and represents zebrafish cd4-1 and cd8a genes. †, Expression of cd8a was below the limit of detection in foxp3a:EGFP-positive thymocytes.
Reference: Kasheta, M., Painter, C. A., Moore, F. E., Lobbardi, R., Bryll, A., Freiman, E., ... & Ceol, C. J. (2017). Identification and characterization of T reg-like cells in zebrafish. Journal of Experimental Medicine, 214(12), 3519-3530.

For Research Use Only | Not For Clinical Use.
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