Mouse Anti-CDH1 Antibody (CBMOAB-00689CR)


Cat: CBMOAB-00689CR
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-00689CR Monoclonal Yeast, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chicken (Gallus gallus), D. melanogaster (Drosophila melanogaster), Frog (Xenopus), Dog (Canis lupus familiaris), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio), Pig WB, ELISA MO00689CR 100 µg
CBMOAB-01178HCB Monoclonal C. elegans (Caenorhabditis elegans) WB, ELISA MO01178HB 100 µg
CBMOAB-69837FYA Monoclonal Zebrafish (Danio rerio) WB, ELISA MO69837FYA 100 µg
MO-AB-01086Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO01086Y 100 µg
MO-AB-09938R Monoclonal Cattle (Bos taurus) WB, ELISA MO09938R 100 µg
MO-AB-29496W Monoclonal Dog (Canis lupus familiaris) WB, ELISA MO29496W 100 µg
MO-NAB-00660W Monoclonal D. melanogaster (Drosophila melanogaster), Frog (Xenopus) FFPE, Block, IF, IP, WB NW0582 100 µg
MO-DKB-03284W Polyclonal Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio) WB, IF, IHC, IHC-P, IP 100 µg
MOFY-0722-FY256 Polyclonal Pig WB, IHC, ICC, IP 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityYeast, C. elegans (Caenorhabditis elegans), Cattle (Bos taurus), Chicken (Gallus gallus), D. melanogaster (Drosophila melanogaster), Frog (Xenopus), Dog (Canis lupus familiaris), Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus), Zebrafish (Danio rerio), Pig
CloneMO00689CR
SpecificityThis antibody binds to Yeast CDH1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionActivator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). During telophase and in the subsequent G1 phase of the cell cycle, recognizes and binds proteins containing a destruction box (D-box) and an additional degradation signal termed the KEN box including ASE1, CDC20, the B-type cyclins CLB2 and CLB3, the polo-like kinase CDC5 and HSL1, and recruits them in a C-box-dependent manner to the APC/C for ubiquitination and subsequent proteolysis. Required for exit from mitosis, cytokinesis and formation of prereplicative complexes in G1. Probably is the target of a BUB2-dependent spindle checkpoint pathway.
Product OverviewMouse Anti-Yeast CDH1 Antibody is a mouse antibody against CDH1. It can be used for CDH1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesAPC/C activator protein CDH1; CDC20 homolog 1; Homolog of CDC twenty 1; CDH1; HCT1; YGL003C
UniProt IDP53197
Protein RefseqThe length of the protein is 566 amino acids long. The sequence is show below: MSTNLNPFMNNTPSSSPLKGSESKRVSKRPISSSSSASLLSSPSRRSRPSTVYGDRYIPSRTDIDFNSIVSISSMASVPALNPSSTEDQVEYQKERQAHETYNTLLKNELFGEMLSKDTVGSESSIDRIKNTRPSTRGNVHAENTTRHGYELERVSTPPPEAAGLEEFSPHSTPVTPRRLFTSQQDEITRPSSNSVRGASLLTYQQRKGRRLSAASLLQSQFFDSMSPVRPDSKQLLLSPGKQFRQIAKVPYRVLDAPSLADDFYYSLIDWSSTDVLAVALGKSIFLTDNNTGDVVHLCDTENEYTSLSWIGAGSHLAVGQANGLVEIYDVMKRKCIRTLSGHIDRVACLSWNNHVLTSGSRDHRILHRDVRMPDPFFETIESHTQEVCGLKWNVADNKLASGGNDNVVHVYEGTSKSPILTFDEHKAAVKAMAWSPHKRGVLATGGGTADRRLKIWNVNTSIKMSDIDSGSQICNMVWSKNTNELVTSHGYSKYNLTLWDCNSMDPIAILKGHSFRVLHLTLSNDGTTVVSGAGDETLRYWKLFDKPKAKVQPNSLIFDAFNQIR.
For Research Use Only | Not For Clinical Use.
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