AibGenesis™ Mouse Anti-cers3 Antibody (MO-AB-02342H)
Cat: MO-AB-02342H

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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Frog (Xenopus laevis), Cattle (Bos taurus) |
| Clone | MO02342C |
| Specificity | This antibody binds to Frog cers3. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene is a member of the ceramide synthase family of genes. The ceramide synthase enzymes regulate sphingolipid synthesis by catalyzing the formation of ceramides from sphingoid base and acyl-coA substrates. This family member is involved in the synthesis of ceramides with ultra-long-chain acyl moieties (ULC-Cers), important to the epidermis in its role in creating a protective barrier from the environment. The protein encoded by this gene has also been implicated in modification of the lipid structures required for spermatogenesis. Mutations in this gene have been associated with male fertility defects, and epidermal defects, including ichthyosis. Alternative splicing results in multiple transcript variants encoding different isoforms. (From NCBI) |
| Product Overview | This product is a mouse antibody against cers3. It can be used for cers3 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | MGC80628 protein; cers3; MGC80628 |
| UniProt ID | Q6GP76 |
| Protein Refseq | The length of the protein is 372 amino acids long. The sequence is show below: MFQTVSDWFWWDRIWLPCNYTWDDLENEEGTGAVSPSQLYVTIPLALVFMLLRYAFERAIATPVAAAMGIKGKVRQKAPVNPVFESFYISCSKHPSHEEIYGLAKKSNRTSIQVERWFRKRRNQDRPAVLKKFQESCWRFTFYLCALVGGVAVLYDKPWFHDVWEVWVGYPKQEVLPSQYWYYVLELSFYWALLFSVASDIRRKDFKVQVVHHLATIFLLNFSWSVKYIRVGTLTLLVHDVSDILLEAAKMCSYADWKRSCNVLFVLFAVVFVISRLIIFPFWIIYATTVYSLYYCPRFFLYYFFNMLMFVLQFLHIYWTYLIFRMVKKVISGNMSGDDRSDKEEKDSDENEDHSLTNGDGKRSIVNGQGDR. |
For Research Use Only | Not For Clinical Use.
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