Mouse Anti-Chicken CDH1 Antibody (MO-AB-01086Y)


Cat: MO-AB-01086Y
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus)
CloneMO01086Y
SpecificityThis antibody binds to Chicken CDH1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Cytoskeleton; Golgi apparatus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionActivator protein that regulates the ubiquitin ligase activity and substrate specificity of the anaphase promoting complex/cyclosome (APC/C). During telophase and in the subsequent G1 phase of the cell cycle, recognizes and binds proteins containing a destruction box (D-box) and an additional degradation signal termed the KEN box including ASE1, CDC20, the B-type cyclins CLB2 and CLB3, the polo-like kinase CDC5 and HSL1, and recruits them in a C-box-dependent manner to the APC/C for ubiquitination and subsequent proteolysis. Required for exit from mitosis, cytokinesis and formation of prereplicative complexes in G1. Probably is the target of a BUB2-dependent spindle checkpoint pathway.
Product OverviewThis product is a mouse antibody against CDH1. It can be used for CDH1 detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative NamesCadherin-1; CDH1
UniProt IDE1C6M9
Protein RefseqThe length of the protein is 887 amino acids long. The sequence is show below: MGRRWGSPALQRFPVLVLLLLLQVCGQRCDEAAPCQPGFAAETFSFSVPQDSVAAGRELGRVSFAACSGRPWAVYVPTDTRFKVNGDGVVSTKRPLTLYGRKISFTIYAQDAMGKRHSARVTVGRHRHRRHHHNHHLQDTTPAVLTFPKHDPGFLRRQKRDWVIPPISCLENHRGPYPMRLVQIKSNKDKESKVYYSITGQGADSPPVGIFIIERETGWLEVTEQLDREKIDRYTLLSHAVSASGQPVEDPMEIIITVMDQNDNKPVFIKEVFVGYIEENAKPGTSVMTVNATDADDAVNTDNGIVSYSIVSQQPPRPHPQMFTIDPAKGIISVLGTGLDRETTPNYTLIVQATDQEGKGLSNTATAIIEVTDANDNIPIFNPTMYEGVVEENKPGTEVARLTVTDQDAPGSPAWQAVYHIKSGNLDGAFSIITDPSTNNGILKTAKGLDYETKSRYDLVVTVENKVPLSVPITLSTASVLVTVLDVNEPPVFVPPIKRVGVPEDLPVGQQVTSYTAQDPDRDMRQKITYRMGSDPAGWLYIHPENGIVTATQPLDRESVHAINSTYKAIILAVDNGIPDTTGTGTLLLLLQDVNDNGPTPEPRSFEICSRQPEKQILSIVDKDLPPHTYPFKAALEHGSSNNWTVEIRGQDELAMGLKKELEPGEYNIFVKLTDSQGKAQVTQVKAQVCECEGTAKNCERRSYIVGGLGVPAILGILGGILALLILLLLLLLFARRRKVEKEPLLPPEDDMRDNVYNYDEEGGGEEDQDYDLSQLHRGLDARPEVIRNDVAPPLMAAPQYRPRPANPDEIGNFIDENLKAADTDPTAPPYDSLLVFDYEGGGSEATSLSSLNSSASDQDQDYDYLNEWGNRFKKLAELYGGGEDDE.
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For Research Use Only | Not For Clinical Use.
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