Mouse Anti-Chicken HMGCR Antibody (MO-AB-02299Y)


Cat: MO-AB-02299Y
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Size:
Conjugate:
 Inquiry
  • Product Details

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityChicken (Gallus gallus)
CloneMO02299Y
SpecificityThis antibody binds to Chicken HMGCR.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionHMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors in the liver, which in turn increases the catabolism of plasma LDL and lowers the plasma concentration of cholesterol, an important determinant of atherosclerosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a mouse antibody against HMGCR. It can be used for HMGCR detection in Western Blot and Enzyme-Linked Immunosorbent Assay.
Alternative Names3-hydroxy-3-methylglutaryl-coenzyme A reductase; HMGCR
UniProt IDV9IPL6
Protein RefseqThe length of the protein is 28 amino acids long. The sequence is show below: GSAMAGSIGGYNAHAANIVTAIYIACGQ.
See other products for " HMGCR "
MO-AB-08741WMouse Anti-Cat HMGCR Antibody (MO-AB-08741W)
MO-AB-41807WMouse Anti-Guinea pig HMGCR Antibody (MO-AB-41807W)
MO-AB-13708RMouse Anti-Cattle HMGCR Antibody (MO-AB-13708R)
MO-AB-23282HMouse Anti-Mallard HMGCR Antibody (MO-AB-23282H)
MO-AB-31133WMouse Anti-Dog HMGCR Antibody (MO-AB-31133W)
MO-AB-26347RMouse Anti-Pig HMGCR Antibody (MO-AB-26347R)
MO-AB-15656YMouse Anti-Sheep HMGCR Antibody (MO-AB-15656Y)
MO-AB-34896WMouse Anti-Ferret HMGCR Antibody (MO-AB-34896W)
MO-AB-00628LMouse Anti-Elephant HMGCR Antibody (MO-AB-00628L)
MO-AB-08369YMouse Anti-Rabbit HMGCR Antibody (MO-AB-08369Y)
For Research Use Only | Not For Clinical Use.
Online Inquiry