Mouse Anti-Chicken SPAG6 Antibody (MO-AB-04113Y)
Cat: MO-AB-04113Y
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Chicken (Gallus gallus) |
Clone | MO04113Y |
Specificity | This antibody binds to Chicken SPAG6. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene. |
Product Overview | This product is a mouse antibody against SPAG6. It can be used for SPAG6 detection in Western Blot and Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Sperm associated antigen 6; SPAG6 |
UniProt ID | M1T4J8 |
Protein Refseq | The length of the protein is 472 amino acids long. The sequence is show below: LREAGVISLLRPLLLDVVPTIQQTAALALGRLAYFNDDLAEAVVKEDILPQLVCSLSEQNRFYKKAAAFVLRAVGKHSPQLAQAIVECGALEALVICLEDFDPGVKEGAAWALGYIARHNSELSQAVVDAGAVPLLVLCIQEPEIALKRIAASTLSDISKHSPELAQTVVDAGAIAYLAQMILNPDAKLKCQVLSALSQIAKHSVDLAELVVEAEIFPVVLTCMKDSDEYVKKNGATLIREIAKHSPELSQFIVNAGGVAAVIDCIGSCKGTVRLPGIMMLGYVAAHSENLSMAVIVSKGIPPLCTCLLEEHEDHIKAAAAWALGQIGRHTPEHARAVAETNVLGTLLSMYMDIRSSEDLQLKAKRALKNILQKCTYLPALEPLLHDAPPNIMKHIVGQFSKVLPHDSKARRLFVTSGGLKKVQEIKAEPGSLLQEYINTINNCYPEEVVRYYSPGYSEMLLERVENYQPVL. |
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For Research Use Only | Not For Clinical Use.
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