Mouse Anti-CSN6 Antibody (CBMOAB-02215HCB)


Cat: CBMOAB-02215HCB
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-02215HCB Monoclonal C. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), O. mykiss (Oncorhynchus mykiss) WB, ELISA MO02215HB 100 µg
CBMOAB-14205FYA Monoclonal Fruit fly (Drosophila melanogaster) WB, ELISA MO14205FYA 100 µg
MO-AB-11090Y Monoclonal O. mykiss (Oncorhynchus mykiss) WB, ELISA MO11090Y 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityC. elegans (Caenorhabditis elegans), Fruit fly (Drosophila melanogaster), O. mykiss (Oncorhynchus mykiss)
CloneMO02215HB
SpecificityThis antibody binds to C. elegans CSN6.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionComponent of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of the SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. The CSN complex plays an essential role in oogenesis and embryogenesis and is required for proper photoreceptor R cell differentiation and promote lamina glial cell migration or axon targeting. It also promotes Ubl-dependent degradation of cyclin E (CycE) during early oogenesis.
Product OverviewMouse Anti-C. elegans CSN6 Antibody is a mouse antibody against CSN6. It can be used for CSN6 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesProtein CSN-6, isoform b; csn-6
UniProt IDC5VUK2
Protein RefseqThe length of the protein is 431 amino acids long. The sequence is show below: MALNAPSGSCSSKVLLHPLVIMQMSEHYSRTKVQQGPTVKKVFGAILGRQNGRQVEAINSFVLKMETEEMAEPVTFSTEHLLQRADQYLEVFPELQVIGLYCAGEDDNLTPEEKPLLSKLTNAVRNSEKAGQIDATLFLKLNSITAGTTRKLPLFAFEADVTDQEKHKPIEWILVSEESERVGVNHIAKLSTKHGKDGKSVGKKHAEAQDAAMSMLQNRVDLIVAYLEKVQDGTLQPNFEILKEANLLAQKLKTIDRYAAEFTDSFEKEEKTMTVFSLMPRLTTLLGNMQNVWNKLSAQRADLLADDGFHGKSTSRWAHPVRFKSQHLGRPQQADECLFQDDDYFDDEDLENDMSGPRRKIHAADSPAGSRRRRVPPRAMNFLGRNSGMQAATDEMELSGQEENMGSNYIPDVPRPSATAHNESDESSQAS.
For Research Use Only | Not For Clinical Use.
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