Mouse Anti-D. melanogaster Atg14 Antibody (CBMOAB-01989FYA)
Cat: CBMOAB-01989FYA
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO01989FYA |
| Specificity | This antibody binds to fruit fly Atg14. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Required for both basal and inducible autophagy. Determines the localization of the autophagy-specific PI3-kinase complex PI3KC3-C1 (PubMed:18843052, PubMed:19050071). Plays a role in autophagosome formation and MAP1LC3/LC3 conjugation to phosphatidylethanolamine (PubMed:19270696, PubMed:20713597). Promotes BECN1 translocation from the trans-Golgi network to autophagosomes (PubMed:20713597). Enhances PIK3C3 activity in a BECN1-dependent manner. Essential for the autophagy-dependent phosphorylation of BECN1 (PubMed:23878393). Stimulates the phosphorylation of BECN1, but suppresses the phosphorylation PIK3C3 by AMPK (PubMed:23878393). Binds to STX17-SNAP29 binary t-SNARE complex on autophagosomes and primes it for VAMP8 interaction to promote autophagosome-endolysosome fusion (PubMed:25686604). Modulates the hepatic lipid metabolism (By similarity). |
| Product Overview | Mouse Anti-D. melanogaster Atg14 Antibody is a mouse antibody against Atg14. It can be used for Atg14 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | CG11877; LD37690p; Atg14 |
| UniProt ID | Q9VAP6 |
| Protein Refseq | The length of the protein is 503 amino acids long. The sequence is show below: MANSSSSDESCKAPDNFRISSASTNGEDEESDVAGYTTKRRPTAATKELLKDANAKDRNATTGMGAHMRCPLCHSCSASRFHCRNCVRNGNITHSQAERPESLTEKQQRYINLQAGLKTFSTRYERLIGQHRSNEDRLMAIKAKRKQLELLQQLISGTGQRLRVLGERRDELRRANAEKRKNLPKYPDKVKMLENYVLDRVEKIEKLRETHLGLLDSIKQAARRSIQQLVTYVFPIAEVVLKEEQQRRASVERTEEAETIAALADAKNTSYIRGKWVFHGSGISEVQYRIVGPSLPANGDYTAYLDWLADNKDDVPKATANEITPSRFEAYRIVGALTYTAQLTQLLSFYLNVRLPHKIAYGDFCRKLLNEEQFRRKISRLNSNIMYLAYTQQVKLRALIEQHTLENLLAILDLERSDLGRYGHLDVNNAPLMKSVDSLLIGIETATESESEDENSLRMDWEAVPSLTPQPELADPNLMPAANQQSTIAFVRMAATSVLRWIK. |
See other products for " ATG14 "
| CBMOAB-00371CR | Mouse Anti-Yeast ATG14 Antibody (CBMOAB-00371CR) |
| MO-AB-13738W | Mouse Anti-Chimpanzee ATG14 Antibody (MO-AB-13738W) |
| MO-AB-51460W | Mouse Anti-Marmoset ATG14 Antibody (MO-AB-51460W) |
For Research Use Only | Not For Clinical Use.
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