AibGenesis™ Mouse Anti-D. melanogaster Cycg Antibody (CBMOAB-14309FYA)


Cat: CBMOAB-14309FYA

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  • Specifications
  • Application Information
  • Target

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO14309FYA
SpecificityThis antibody binds to fruit fly Cycg.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCyclin with roles in multiple processes including transcription, meiotic recombination repair, cell cycle regulation, and promotion of normal growth and metabolism (PubMed:18667003, PubMed:18286205, PubMed:21311225, PubMed:22976300, PubMed:25995770, PubMed:26274446). Binds to the promoter region of the homeobox gene Abd-B and is involved in maintaining Abd-B expression in the pupal epithelium (PubMed:18667003, PubMed:18286205). Involved in the transcriptional repression of the homeotic genes Scr and Ubx (PubMed:25995770). Plays a role in meiotic recombination repair of DNA double-strand breaks which ensures efficient translation of grk and promotes grk activity in the oocyte, leading to oocyte dorso-ventral axis formation following secretion of grk from the oocyte and its binding to Egfr in the directly overlying follicle cells (PubMed:23121330, PubMed:22976300). Negatively regulates the binding of serine/threonine-protein kinase Akt1 to the protein phosphatase 2A subunit wdb, promoting normal growth and metabolism (PubMed:26274446). Required for the formation of bilateral symmetry (PubMed:21998598). Negatively regulates cell cycle progression by preventing G1 to S transition and retarding S-phase progression (PubMed:21311225). (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-D. melanogaster Cycg Antibody is a mouse antibody against Cycg. It can be used for Cycg detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCyclin G, isoform A; EC 2.7.1.-; Cyclin G, isoform B; EC 2.7.1.-; Cyclin G, isoform C; EC 2.7.1.-; Cyclin G, isoform D; EC 2.7.1.-; LD46284p; CycG
UniProt IDQ95TJ9
Protein RefseqThe length of the protein is 566 amino acids long.
The sequence is show below: MSVPVRYSSAAAEYAAEVDCELESTLQQQQQLHLQQQYEQYQHYQYQREQDIAYYCQLQAARQQEQLMQQRTSMSSSVMPGLALPQDHQDHPAALLNGPHNNNIGLAMDAHSINAILVDDEQPSTSAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSLKKLEDQLHALTSDELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELENRLEILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQNKAPYKQRLVWKLSSRTLRVLRPINRFSSDLPTIEEGIPNALDDGLRSRTESISSEEEEDWPTSPIIPIFEQC.
For Research Use Only | Not For Clinical Use.
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