Mouse Anti-D. melanogaster Drosha Antibody (CBMOAB-15186FYA)
Cat: CBMOAB-15186FYA
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To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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- Product Details
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO15186FYA |
| Specificity | This antibody binds to fruit fly Drosha. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. |
| Product Overview | Mouse Anti-D. melanogaster Drosha Antibody is a mouse antibody against Drosha. It can be used for Drosha detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Drosha; EC 3.1.26.3; LD20030p; Ribonuclease; drosha |
| UniProt ID | Q7KNF1 |
| Protein Refseq | The length of the protein is 1327 amino acids long. The sequence is show below: MYQPPLPPPPVQPAPPPPPPPPEEDLSPPGVGVPSHNYSSNESHSQSSKSLDYVYPETPAPYASSVPSYDPYQQPPAYGYEGYAYNEQAQKYGGQESHYQYQYPASGSSFLYESYKYPDRYPAYSSNYRPPSERQRYTSNSSSQGYHHYPGYSSGRRYEQRHDQEHRQIQDSRYAHEPRHGHYAHRQAKGSQHGYYGSAARNQVSDDYSPRGHHERERNETLEKTRAKPKVETERDRLLRQWCSNFCEKPEDYVKKMNALSEADAPVESWVRSSPAELYYERTKSENEVRGRARLQKLCTLFDEELLQRAKRVREKLPVYVPPPRKARRRVCKHKHKSEACSSSSSSDDDSDEDAFKIEQDCCMEELSRKVQHPQRVHADLWHNDAGEMNDGPLCRCSAKSRRIGIRHGIYPGETGYKLCDPNSNNAGKLFHYRISISPPTNFLTKTPTIIKHDEHEFLFEGFSLLSHVRLSDLPVCKVIRFNIEYTIEYEEEKMPENFTIHELDIFFKYLFHELLELVDFNLMPNLPSGNVEESCPAFHFFPRFVRDLPDNGKEVLAMVEVLRYLLDNSAQLVERQQLLHLNQISQSEWQNYVDFIKGMLVTKPGYKPCSLRVDQLDRNNSDLPECVDRETGISHPAIVHFGICHPQLSYAGNPEYQKAWREYVKYRHLMANMSKPSFKDKRKLEEKEQRLQEMRTQGRMKRNITVAISSEGFYRTGIMCDVVQHAMLIPVLTGHLRFHKSLDLLEESIGYRFKNRYLLQLALTHPSYKENYGTNPDHARNSLTNCGIRQPEYGDRKIHYMNTRKRGINTLVSIMSRFGKEHETVSNITHNERLEFLGDAVVEFLSSIHLFFMFPELEEGGLATYRAAIVQNQHLALLAKKLQLEEFMLYAHGSDLCHELELRHAMANCFEALMGALLLDGGIKVADEVFTDALFRQDEKLLSIWKNLPEHPLQEQEPLGDRSCIDSYRVLKELTKFEDSIGIKFKHIRLLARAFTDRSIGFTHLTLGSNQRLEFLGDTVLQLICSEYLYRHFPEHHEGHLSLLRSSLVNNRTQAVVCDDLGMPKYAVYANPKADLKTKDRADLLEAFLGALYVDKGLLYCEQFCHVCLFPRLQLFIMNQDWNDPKSKLQQCCLTLRTMDGGEPDIPYYKVVEASGPTNTRVYKVAVYFRSKRLATSSGSSIQQAEMNAAKQALENSRDLFPQLDHQKRVIAKSIKKQTGNELDNDSDRQHQEEKIKRPKYATPLQDESHLPKQYRMHENISSDELPEDEDFESTAPKSPTMPLRSNRSGSSSSSSSSDSDGSTSSPKCKRRLKKCSSVSSKSSLG. |
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For Research Use Only | Not For Clinical Use.
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