Ribonuclease 3 isoform 2
This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer.
Mouse Anti-Drosha Antibody (CBMOAB-15186FYA) (CAT#: CBMOAB-15186FYA)
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- Host species: Mouse
- Species Reactivity: Fruit fly (Drosophila melanogaster), Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: Drosha
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Drosha, EC 3.1.26.3, LD20030p, Ribonuclease, drosha
Mouse Anti-DROSHA Antibody (MO-AB-20627W) (CAT#: MO-AB-20627W)
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- Host species: Mouse
- Species Reactivity: Chimpanzee (Pan troglodytes), Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: Drosha ribonuclease III
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Drosha, ribonuclease type III, DROSHA
Mouse Anti-DROSHA Antibody (MO-AB-54508W) (CAT#: MO-AB-54508W)
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- Host species: Mouse
- Species Reactivity: Marmoset, Rhesus (Macaca mulatta)
- Application: WB, ELISA
- Protein: Submitted name: Ribonuclease 3 isoform 1
- Size: 0.5mg, 1mg, 200µg
- Conjugate: Alexa Fluor 350, AP, APC, Biotin, Consult us more, Cy3, Cy5, Cy5.5, Cy7, FITC, HRP, NONE, PE, PerCP
- Alternative Names: Ribonuclease 3 isoform 1, DROSHA
For Research Use Only | Not For Clinical Use.
