Mouse Anti-D. melanogaster Hspb8 Antibody (CBMOAB-20842FYA)


Cat: CBMOAB-20842FYA
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster)
CloneMO20842FYA
SpecificityThis antibody binds to fruit fly Hspb8.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationOther locations; Nucleus; Cytosol

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThe protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
Product OverviewMouse Anti-D. melanogaster Hspb8 Antibody is a mouse antibody against Hspb8. It can be used for Hspb8 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCG14207-PB, isoform B; RE23625p; RE52196p; HspB8; CG14207-RB
UniProt IDQ8IQW5
Protein RefseqThe length of the protein is 192 amino acids long.
The sequence is show below: MAEANKRNIPIKLGDFSVIDTEFSNIRERFDSEMRKMEEEMAKFRHELMNREANFFESTSSTKKTTTTSSTTNSALPSRIPKQQNYVSDISSPLIQDEGDNKVLKLRFDVSQYAPEEIVVKTVDQKLLVHAKHEEKSDTKSVYREYNREFLLPKGVNPESIRSSLSKDGVLTVDAPLPALTAGETLIPIAHK.
For Research Use Only | Not For Clinical Use.
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