Mouse Anti-Dog CD8A Antibody (MO-AB-29492W)


Cat: MO-AB-29492W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityDog (Canis lupus familiaris)
CloneMO29492W
SpecificityThis antibody binds to Dog CD8A.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionCD8A (CD8a Molecule) is a Protein Coding gene. Diseases associated with CD8A include Cd8 Deficiency, Familial and Primary Cutaneous Aggressive Epidermotropic Cd8+ T-Cell Lymphoma. Among its related pathways are Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers and T-Cell Receptor and Co-stimulatory Signaling. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and coreceptor activity.
Product OverviewMouse Anti-Dog CD8A Antibody is a mouse antibody against CD8A. It can be used for CD8A detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesT-cell surface glycoprotein CD8 alpha chain; CD antigen CD8a; CD8A
UniProt IDP33706
Protein RefseqThe length of the protein is 239 amino acids long.
The sequence is show below: MASRVTALLLPLALLLRAAAASGPSRFRMTPPKVVGQLHAQVELQCQVLLSTAAPGCSWLYQRNEPAARPVFLMYISQSRAKPAEGLDTKHISGQKKTDSTYSLTLSRFRKEDEGYYFCSVLSNSILYFSPFVPVFLPVKPPTTPAPRPPTRAPTNASKPVSPRGETCRPAAGSAVKTSGLDFACEIYIWAPLAGTCAVLLLSLVITIICNHRNRRRVCKCPRPVVRPGGKPSPSEKYV.

Reference

Reference1. Eschke, M., Moore, P. F., Chang, H., Alber, G., & Keller, S. M. (2023). Canine peripheral blood TCRαβ T cell atlas: Identification of diverse subsets including CD8A+ MAIT-like cells by combined single-cell transcriptome and V (D) J repertoire analysis. Frontiers in Immunology, 14.
2. Shao, X., Wang, X., Xu, F., Dai, T., Zhou, J. G., Liu, J., ... & Liu, Y. (2022). In vivo biocompatibility and degradability of a Zn-Mg-Fe alloy osteosynthesis system. Bioactive Materials, 7, 154-166.
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For Research Use Only | Not For Clinical Use.
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