Mouse Anti-Drosophila p53 Antibody (AA 282-386)


Cat: MO-NAB-00834W
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityD. melanogaster (Drosophila melanogaster)
CloneNW0756
SpecificityThis antibody is binds to D. melanogaster p53.
ImmunogenRecombinant GST fusion protein of Drosophila p53 (aa 282-386; common to all isotypes).
EpitopeThe epitope is in the AA 282-386 of p53
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use

Application Information

ApplicationIF, IHC, IP, WB

Target

IntroductionActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression.
Product OverviewThis product is a Mouse antibody against the AA 282-386 of the p53. It can be used for p53 detection in Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot.
Alternative NamesGH11591p; P53 tumor suppressor-like protein; P53-like regulator of apoptosis and cell cycle; Transcription factor; Transcription factor p53; p53, isoform A; p53, isoform C; p53; prac
Gene ID2768677
UniProt IDQ9N6D8
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For Research Use Only | Not For Clinical Use.
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