AibGenesis™ Mouse Anti-Egr Antibody (CBMOAB-16039FYA)
Cat: CBMOAB-16039FYA
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- Product List
- Specifications
- Application Information
- Target
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster) |
| Clone | MO16039FYA |
| Specificity | This antibody binds to fruit fly Egr. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Plasma Membrane; Other locations; Extracellular region or secreted |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Cytokine which acts as a ligand for wgn (PubMed:12894227). Also acts as a ligand for grnd (PubMed:25874673). Induces apoptosis by triggering JNK signaling (PubMed:12176339, PubMed:12065414, PubMed:12894227). Required for JNK-dependent non-autonomous apoptosis through release from apoptotic cells and activation of apoptosis in neighboring cells (PubMed:24066226). Required for JNK-independent damage-induced apoptosis in the embryonic central nervous system through regulation of the pro-apoptotic gene hid (PubMed:25754009). Involved in the innate immune response to extracellular pathogens (PubMed:17381241). Plays a role in the melanization immune response through its involvement in the rupture of crystal cells and subsequent release of prophenoloxidase (PubMed:17356067). Following UV-induced epidermal damage, released from apoptotic epidermal cells, binds to the wgn receptor on nociceptive sensory neurons and plays a role in development of thermal allodynia, a responsiveness to subthreshold thermal stimuli which are not normally perceived as noxious (PubMed:19375319). Involved in glial cell division induced by neuronal programmed cell death and injury (PubMed:19019992). Has tumor suppressor activity and eliminates oncogenic cells from epithelia, thereby maintaining epithelial integrity (PubMed:19289090). (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster Egr Antibody is a mouse antibody against Egr. It can be used for Egr detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | DARTH; Eiger; Eiger, isoform A; egr; darth |
| UniProt ID | Q8MUJ1 |
| Protein Refseq | The length of the protein is 415 amino acids long. The sequence is show below: MTAETLKPFITPTSANDDGFPAKATSTATAQRRTRQLIPLVLGFIGLGLVVAILALTIWQTTRVSHLDKELKSLKRVVDNLQQRLGINYLDEFDEFQKEYENALIDYPKKVDGLTDEEDDDDGDGLDSIADDEDDDVSYSSVDDVGADYEDYTDMLNKLNNAHTGTTPTSETTAEGEGETDSASSASNDDNVFDDFTSYNAHKKKQERKSRSIADVRNEEQNIQGNHTELQEKSSNEATSKESPAPLHHRRRMHSRHRHLLVRKGESLLSARSEDSRPAAHFHLSSRRRHQGSMGYHGDMYIGNDNERNSYQGHFQTRDGVLTVTNTGLYYVYAQICYNNSHDQNGFIVFQGDTPFLQCLNTVPTNMPHKVHTCHTSGLIHLERNERIHLKDIHNDRNAVLREGNNRSYFGIFKV. |
For Research Use Only | Not For Clinical Use.
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