Mouse Anti-Eif4G2 Antibody (CBMOAB-16107FYA)


Cat: CBMOAB-16107FYA
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-16107FYA Monoclonal Fruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chicken (Gallus gallus), Frog (Xenopus laevis), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries) WB, ELISA MO16107FYA 100 µg
CBMOAB-41644FYA Monoclonal Rhesus (Macaca mulatta) WB, ELISA MO41644FYA 100 µg
MO-AB-01734Y Monoclonal Chicken (Gallus gallus) WB, ELISA MO01734Y 100 µg
MO-AB-03246H Monoclonal Frog (Xenopus laevis) WB, ELISA MO03246C 100 µg
MO-AB-07994Y Monoclonal Rabbit (Oryctolagus cuniculus) WB, ELISA MO07994Y 100 µg
MO-AB-11943R Monoclonal Cattle (Bos taurus) WB, ELISA MO11943R 100 µg
MO-AB-15153Y Monoclonal Sheep (Ovis aries) WB, ELISA MO15153Y 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Cattle (Bos taurus), Chicken (Gallus gallus), Frog (Xenopus laevis), Rabbit (Oryctolagus cuniculus), Rhesus (Macaca mulatta), Sheep (Ovis aries)
CloneMO16107FYA
SpecificityThis antibody binds to fruit fly Eif4G2.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionTranslation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.
Product OverviewMouse Anti-D. melanogaster Eif4G2 Antibody is a mouse antibody against Eif4G2. It can be used for Eif4G2 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesEukaryotic translation initiation factor 4G2; eIF4G2; ofs
UniProt IDQ9VCH1
Protein RefseqThe length of the protein is 2072 amino acids long.
The sequence is show below: MFPQQGGGGKGTRPQSTHQQNHNHQAQHHQATHSHHHHLQQQQEQQQSHAVFVPNHSGLHHHQQQHLLQQQQQQHQQQAAVAAAHLQQHIQQQQQQQVQAQAQAHHQPVIFYNTQPSYAAHSAAVNNSANGGGATLQLSAAASSNTLGHPLTGGHHGGANGVAPGSNMPRALSNPTLPPHFQQSAGLIAPAGGNAGGPYISATYIPINQTGPLMGMQPAVTFPTNGAAGASFYAAAPPPPQQKQLPPTAQQQGPGGAPGAAQTPTLAYYQLGPNAQNSAGNNVVSGANTHRGNMRGGQRSTPTAQHTNYFTAYTMAPGNAQRPAPTNVAPMMNSRSGALNGAAAFHHLPHNFGIPSLALGPPAGMTTPILAPAGMQAPPPQPPGGLHTFAPHLQSNSATTLPSVPSVTGVPAVASGFSTTSLPTPSVTTAPQLGANSDKVCKRKYAIPIIHPDTMENVMDGWKRSVFIKKDSNSTLTQHTDLDTALDDNSTLCLYQAPTLMDSGSGSSLLSGAMVDQQMQTVKPASSLKQSVSLEKVPEAVYCKDAVGQDVHPSPPPKSTDKDQISVIVKDILAHSGNAEDHLSFWQYSDVDNVTETHNSLPLVQSDLPDTTDTCQQPVLFQEQAKKQRPKLANKQSTATPASIANDVAEAAASGCPGVSILSRGQSMVTPAGPSTPPPPSRVAQQKSTKSIVTTAVAASVKPTTGSPNRKSSIQAATSTTTSSGASSSTASTPTHASSKLKQQPVNNLQHGKQIPGKVSTPALPPTASRISAAVTLLAGTANITTTTNSSKKQRQAQKRARELEKKKQKSSITSTTSTQGQNNNGKGNGNGNAALEINTNSNNAATVTTTSMSTLTTTTTATAPTTKQETAAVDDKETAQPTTDTLSATSNNTKVSSILRDKKTMLNPKEQLTSHNNNNNNNNEDGIEAKVESDPESDIKDDSMSNITGEKSEKHLANEEIVAKFLQKDSPDTSVVHAETQQLQFLNSSSSVCEEDEPVPVISEGVTKTEENAEAEIKFGDFHEDPRNDTGFICSSTWSSSTISKAAEDDSSQSSRSADNVDCAPKVVEQISEEKSASSTKSSPVHKATGSGPGSPKTKELKSKSPSPIPVPQVPKNYRYSIETLRELAKRRDSRKPPMVPCQKGDCISQLFVSRQQQPQQHHGQHIQQYQHMSFNESLDYVPGKRGRGHGPNKKHHDQHQQMGGSSGMGSGSGGGGGISNSSQRHMDIIRVQLSLKEEIKLSECENAWQPGTLRRVSMAGGQDEDDDVEGVLKKVRGILNKLTPDNFEVLLKEMSSIKMDNEAKMTNVMLLIFEKTISEPNFAPTYARFCKVLFHEIKAENKSLFTSSLITRIQHEFESNVNDANAKSKKLQPTMERINQCSDPAKKAELRAEMEDLEYQFRRRAWGTVRFIGELFKLQSLTNDRVLNCVESLLEHGCEEKLEYMCKLLTTVGHLLESSLPEHYQLRDRIEKIFRRIQDIINRSRGTSHRQQVHIKISSRVRFMMQDVLDLRLRNWDQPATHQSGQQGGRGQRHKQHDDSKDQSHSTGGGRGGGMNQHQQSSTHHQHQKHNQHGHDGGNYFMQKMPNKQHHENQTLSIDPSKLRFSNSSATDDSIAKLGNSSHYQWRNVGNRPVSSTQVNASNAPPPTSLLKRPGQNYKFLPYQQPSAVAGTANAPAGGNKSNVEVNDAFDGKQCQGLITKLVEEALNTREWQPEVLSIWRSHSGSQQSKTLFHLLTDYLHKSTVKRQHRQACGNIFAYLMDKDAVEKEIFEEAYSRFGDDFPDLLVDVPNGWGYVFEFLGPIIHSGHLDLKDVWQRRWLDDFFFAERFVYAFVSYFVQEFGAAYARKLWHNDYKLDRGQLFWSDVRKYREFVQSHSFYFLDNGPGQNQGHAKVKAPTTPRSPVEHVERIRHLLAISCDMAIDYINTNVAINDKFVRQLTRFLCCDFALTVMTNTHNNIKSGGNSKPLQLNTESFRSCCTPLLRLCIDAQEALEIACIDEAVDALQQHFMTEYEDDMAAGETICSTFSVLYESEVIPKESFDKWYKLEMAHSRAYRRPFIDKLRGFIEEM.
For Research Use Only | Not For Clinical Use.
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