Mouse Anti-Elephant SNCA Antibody (MO-AB-01433L)


Cat: MO-AB-01433L
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityElephant (Loxodonta africana)
CloneMO01433L
SpecificityThis antibody binds to Elephant SNCA.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationPlasma membrane; Cytosol; Cytoskeleton; Mitochondrion; Nucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionAlpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer''s disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene.
Product OverviewThis product is a mouse antibody against SNCA. It can be used for SNCA detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesSynuclein Alpha; Synuclein, Alpha (Non A4 Component Of Amyloid Precursor); Alpha-Synuclein; PARK1; NACP; Parkinson Disease (Autosomal Dominant, Lewy Body) 4; Non A4 Component Of Amyloid Precursor; Non-A4 Component Of Amyloid Precursor
UniProt IDG3T7Z3
Protein RefseqThe length of the protein is 140 amino acids long. The sequence is show below: MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVTTVAEKTKEQVTNVGEAVVTGVTAVAQKTVEGAGSIAAATGFGKKDQMGKGEEGAPQEGILENVPVDPDNEAYEMPSEEGYQDYEPEA.
For Research Use Only | Not For Clinical Use.
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