Mouse Anti-Elephant USB1 Antibody (MO-AB-01602L)
Cat: MO-AB-01602L
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Elephant (Loxodonta africana) |
Clone | MO01602L |
Specificity | This antibody binds to Elephant USB1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Cellular Localization | Extracellular region or secreted; Nucleus; Other locations |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. |
Product Overview | This product is a mouse antibody against USB1. It can be used for USB1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | U6 snRNA phosphodiesterase; EC 3.1.4.-; USB1 |
UniProt ID | G3SQ47 |
Protein Refseq | The length of the protein is 269 amino acids long. The sequence is show below: MNAGPLVGYSSSGSEDEAKPRASSGRRSPGGATIMHSAGQTPLASQRLPVPDSVLNMFPSTEEGPEDDSAKHGGRVRTFPHERGNWATHVYIPCEHSKCLSIPDEKIVPREDYFCSRSSLAPPPFIWLSLSNLLRYYYLLTFWNVAFFLLLNFRFFFTANRVKIYTNQEKTRTFVGLEVTSGHAQFLSLVSEVDRVMEEFALTTFYQNPSFHVSLAWCVGDARPQLEGQCLHNLQEIVDEFEDSELLLRVYAEQIRCKSGNKFFSLPLK. |
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For Research Use Only | Not For Clinical Use.
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