AibGenesis™ Mouse Anti-Fib Antibody (CBMOAB-16808FYA)


Cat: CBMOAB-16808FYA

Certificate of Analysis Lookup
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Lot Number

  • Product List
  • Specifications
  • Application Information
  • Target
Sub Cat Clonality Species Reactivity Application Clone Conjugate Size  
CBMOAB-16808FYA Monoclonal Fruit fly (Drosophila melanogaster), Horse (Equus caballus), Malaria parasite WB, ELISA MO16808FYA 100 µg
MO-AB-12624H Monoclonal Malaria parasite WB, ELISA MO12624C 100 µg
MO-AB-44766W Monoclonal Horse (Equus caballus) WB, ELISA MO44766W 100 µg

Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFruit fly (Drosophila melanogaster), Horse (Equus caballus), Malaria parasite
CloneMO16808FYA
SpecificityThis antibody binds to fruit fly Fib.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus; Other locations

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionS-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ105me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus. (From uniprot, under CC BY 4.0)
Product OverviewMouse Anti-D. melanogaster Fib Antibody is a mouse antibody against Fib. It can be used for Fib detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesrRNA 2'-O-methyltransferase fibrillarin; EC 2.1.1.-; Histone-glutamine methyltransferase; Fib
UniProt IDQ9W1V3
Protein RefseqThe length of the protein is 344 amino acids long.
The sequence is show below: MGKPGFSPRGGGGGGGGGGGGFRGRGGGGGGGGGGFGGGRGRGGGGDRGGRGGFGGGRGGGGRGGGGGGGRGAFGGRGGGGGRGGGGRGGGGRGGGGRGGGAGGFKGGKTVTIEPHRHEGVFIARGKEDALVTRNFVPGSEVYGEKRISVETNGEKIEYRVWNPFRSKLAAAVLGGVEQIHMPPGSKVLYLGAASGTTVSHVSDVVGPEGLVYAVEFSHRSGRDLINVAKKRTNIIPIIEDARHPHKYRMLVGMVDTIFADVAQPDQGRIVALNAQHFLKNGGHFVISIKASCIDSTAQPEAVFAAEVKKMQADKLKPQEQLTLEPYERDHAVVVGVYRPPPKQ.
For Research Use Only | Not For Clinical Use.
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