AibGenesis™ Mouse Anti-Foxo Antibody (CBMOAB-16933FYA)
Cat: CBMOAB-16933FYA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
- Product List
- Specifications
- Application Information
- Target
| Sub Cat | Clonality | Species Reactivity | Application | Clone | Conjugate | Size | |
| CBMOAB-16933FYA | Monoclonal | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Purple sea urchin (Strongylocentrotus purpuratus), Silkworm (Bombyx mori) | WB, ELISA | MO16933FYA | 100 µg | ||
| MO-AB-06116Y | Monoclonal | A. aegpti (Aedes aegpti) | WB, ELISA | MO06116Y | 100 µg | ||
| MO-AB-30699H | Monoclonal | Purple sea urchin (Strongylocentrotus purpuratus) | WB, ELISA | MO30699C | 100 µg | ||
| MO-AB-69834W | Monoclonal | Silkworm (Bombyx mori) | WB, ELISA | MO69834W | 100 µg |
Specifications
| Host species | Mouse (Mus musculus) |
| Species Reactivity | Fruit fly (Drosophila melanogaster), A. aegpti (Aedes aegpti), Purple sea urchin (Strongylocentrotus purpuratus), Silkworm (Bombyx mori) |
| Clone | MO16933FYA |
| Specificity | This antibody binds to fruit fly Foxo. |
| Format | Liquid or Lyophilized |
| Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
| Purity | > 90% was determined by SDS-PAGE |
| Purification | Purified with Protein A or G affinity chromatography |
| Cellular Localization | Nucleus; Other locations; Cytosol |
Application Information
| Application | WB, ELISA |
| Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
| Introduction | Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis. (From uniprot, under CC BY 4.0) |
| Product Overview | Mouse Anti-D. melanogaster Foxo Antibody is a mouse antibody against Foxo. It can be used for Foxo detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
| Alternative Names | Forkhead box protein O; dFOXO; Protein FKHR; foxo; Afx |
| UniProt ID | Q95V55 |
| Protein Refseq | The length of the protein is 613 amino acids long. The sequence is show below: MMDGYAQEWPRLTHTDNGLAMDQLGGDLPLDVGFEPQTRARSNTWPCPRPENFVEPTDELDSTKASNQQLAPGDSQQAIQNANAAKKNSSRRNAWGNLSYADLITHAIGSATDKRLTLSQIYEWMVQNVPYFKDKGDSNSSAGWKNSIRHNLSLHNRFMRVQNEGTGKSSWWMLNPEAKPGKSVRRRAASMETSRYEKRRGRAKKRVEALRQAGVVGLNDATPSPSSSVSEGLDHFPESPLHSGGGFQLSPDFRQRASSNASSCGRLSPIRAQDLEPDWGFPVDYQNTTMTQAHAQALEELTGTMADELTLCNQQQQGFSAASGLPSQPPPPPYQPPQHQQAQQQQQQQSPYALNGPASGYNTLQPQSQCLLHRSLNCSCMHNARDGLSPNSVTTTMSPAYPNSEPSSDSLNTYSNVVLDGPADTAALMVQQQQQQQQQQQLSASLEGQCLEVLNNEAQPIDEFNLENFPVGNLECNVEELLQQEMSYGGLLDINIPLATVNTNLVNSSSGPLSISNISNLSNISSNSGSSLSLNQLQAQLQQQQQQQQAQQQQQAQQQQQQHQQHQQQLLLNNNNNSSSSLELATQTATTNLNARVQYSQPSVVTSPPSWVH. |
For Research Use Only | Not For Clinical Use.
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