Mouse Anti-Frog abl1 Antibody (MO-AB-01147H)
Cat: MO-AB-01147H
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Frog (Xenopus laevis) |
Clone | MO01147C |
Specificity | This antibody binds to Frog abl1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA-binding activity that is regulated by CDC2-mediated phosphorylation, suggesting a cell cycle function. This gene has been found fused to a variety of translocation partner genes in various leukemias, most notably the t(9;22) translocation that results in a fusion with the 5' end of the breakpoint cluster region gene (BCR; MIM:151410). Alternative splicing of this gene results in two transcript variants, which contain alternative first exons that are spliced to the remaining common exons. |
Product Overview | This product is a mouse antibody against abl1. It can be used for abl1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | Tyrosine-protein kinase Abl1 isoform b variant 1 |
UniProt ID | V5NT95 |
Protein Refseq | The length of the protein is 1115 amino acids long. The sequence is show below: MGQQPGKVLGEQRRPSLPVLPFIKGGGKKDSAKHAGPHCNVFVEHEALQRPTVSDIEPQGLSEAARWNSKENLLSGPSENDPNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVNSPEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYVSSDSRFNTLAELVHHHSTVSDGLITTLHYPAPKRNKPTIYGVSPNYDKWEIERTDITMKHKLGGGQYGEVYEGVWKKYNLTVAVKTLKEDTMEVEEFLKEAAVMKEVKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLRDCNRQEVTAVVLLHMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMTGDTYTAHAGAKFPIKWTAPESLAYNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCPEKVYELMRACWQWNPLDRPSFAEIHQAFETMFQESSISDEVEKELGKKGLKVTVSNLLQAPELPTKTRTTRRVPESKDENADIASIRAAGELDAFEPESAVSPLLPRKEKGAGDGGLPDDDRLLVKDKKTNLFFSTLIKRKKKTAPTPPKRSSSFRDMEGHSERRCTEGEGKEANNGGDLLDAFKFSTNGTALSNGSIQGSIGFLSSQWKKSSAMIGRQTSAGDEEAICSTGKRFLRSCSASCMPHGAKDTEWKSVTLPREMTSSRCLLDTPGSDSLKKAEKPALPRKRGNESKPEGTRGTVTPPPRLPKKCEDPIDEVFKDADPSPNSSPPSLTPKLPRRKQAGPAGAPLQKEEASNIRLGSDTGPSTKQTSLAGKSEAELRLRRPKTSEPVSRDKVKVLKVKPSPPLPLSCIGSSSSTSSNLGKASKPPSQSPSHDTSPSEPKHKPTSQTDELSKTPPPVPDSSKKPLLLSSSKPQVTGKLSGGDQSQQPAPSSYSSTAFVPLISTRVSLRKTRQPPEKHSSPVTKETVLASTECLKAAITRNSEQMASHSSVLEAAKNLHAFCTSYVDSIQQMRNKFAFREAISKLENSLRDLQICPAPAAAGGGAATSQDFSKLLTSVKEISDVVQR. |
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For Research Use Only | Not For Clinical Use.
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