Mouse Anti-Frog blnk Antibody (MO-AB-01874H)


Cat: MO-AB-01874H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO01874C
SpecificityThis antibody binds to Frog blnk.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene.
Product OverviewThis product is a mouse antibody against blnk. It can be used for blnk detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesLOC398328 protein; blnk; LOC398328
UniProt IDQ5U4V8
Protein RefseqThe length of the protein is 549 amino acids long.
The sequence is show below: MDKFREISAPAGQKLRQLQKIVHDIKKNDGGIMQKIKKFQNDQVALFCKTGKETWDRIKSKPPPPPTVPQRDYVLGEVEEEFDEWSDESDSEYVNPDPQSDSETYVIPAEEDDNYEPPPTEPVKTIPSSFTFSSSGGGYADKQGNRQLPPVPDQANKTPMRLQPNVNQTFPKVSPPLPKPNQRLHNGTKSLPLPVPKPPLPKQPVTPRPHAVSQNQSASKKSITPPKQQYVDEEEYIVPGEEEDNYIEPTQDPPFPPPVVNRSSKPVPPALGKNHQTSHNPVVYEVPESEQKPPSPAKRNSLPLPRINSSSTAEPACEDEYEPCDELETLAVGNKKNTPNIPSPLPRKSKPLPAWSTGFTPRDINGNTDKSTAADRNRTPSVGADLPPLPHSAQKLPIPLPKTNMQKPPEVPNRYVSNPSRKMSHSSPEEEAGVLNKEWYAASCDRKKAEEALYTSCKDGSFLVRQSSGQDPKQPYTLVVFYNRKVYNIPVRFIEETRQYALGREKSGEEKFSSVAEMIMSHQRMPLVLIDSQNNTKDSTKLRQAIKVS.
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For Research Use Only | Not For Clinical Use.
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