Mouse Anti-Frog dph5 Antibody (MO-AB-03083H)


Cat: MO-AB-03083H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO03083C
SpecificityThis antibody binds to Frog dph5.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene.
Product OverviewThis product is a mouse antibody against dph5. It can be used for dph5 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesCgi-30-prov protein; dph5
UniProt IDQ7SYW0
Protein RefseqThe length of the protein is 241 amino acids long.
The sequence is show below: MLYLIGLGLGDEKDVTLKGLEVIRSCARVYLEAYTSILTVRKETLEEFYGRELILADRETVEQEADEILRDAAVSDVALLVVGDPFGATTHSDLVLRAAKAGIQHHVIHNASIMTAVGCCGLQLYNFGETVSIVFWTDMWKPESFYDKIRRNRLSGMHTLCLLDIKVKEQSIENLMNFNGEHNLCGTGSCWCFGPENISRDPAAAKLGGLWGSSSLSGDQWLYAPFRTGHAKALCCGTIHF.
For Research Use Only | Not For Clinical Use.
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