Mouse Anti-Frog impa1 Antibody (MO-AB-04492H)


Cat: MO-AB-04492H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO04492C
SpecificityThis antibody binds to Frog impa1.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13.
Product OverviewThis product is a mouse antibody against impa1. It can be used for impa1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesMGC83403 protein; impa1; MGC83403
UniProt IDQ6GM60
Protein RefseqThe length of the protein is 280 amino acids long.
The sequence is show below: MEDRWQECMDFAVSIARKAGSVVCAALKEDVSIMVKSSPADLVTATDQKVEEMIISSIKEKYPSHSFIGEESVAAGAGSTLTDNATWIIDPIDGTTNFVHRFPFVAVSIGFAVNKQVEFGVVYSCVEDKMYTGRKGKGSFCNGQKLQVSGQKDITKSMIITELGSNRNPEVIKTVLSNMERLLCIPIHGIRAVGTAAVNMCLVATGGADAYYEMGLHCWDMAAASVIVTEAGGTILDATGGLFDLMSCRIISASSREIAERIAKELQIIPLERDDGISTN.
For Research Use Only | Not For Clinical Use.
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