Mouse Anti-Frog impa1 Antibody (MO-AB-04492H)
Cat: MO-AB-04492H
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- Product Details
Specifications
Host species | Mouse (Mus musculus) |
Species Reactivity | Frog (Xenopus laevis) |
Clone | MO04492C |
Specificity | This antibody binds to Frog impa1. |
Format | Liquid or Lyophilized |
Storage | Store at 4°C: short-term (1-2weeks) Store at -20°C: long-term and future use |
Purity | > 90% was determined by SDS-PAGE |
Purification | Purified with Protein A or G affinity chromatography |
Application Information
Application | WB, ELISA |
Application Notes | ELISA: 1:1000-1:3000 Other applications are to be developed. The optimal dilution should be determined by the end user. |
Target
Introduction | This gene encodes an enzyme that dephosphorylates myo-inositol monophosphate to generate free myo-inositol, a precursor of phosphatidylinositol, and is therefore an important modulator of intracellular signal transduction via the production of the second messengers myoinositol 1,4,5-trisphosphate and diacylglycerol. This enzyme can also use myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. This enzyme shows magnesium-dependent phosphatase activity and is inhibited by therapeutic concentrations of lithium. Inhibition of inositol monophosphate hydroylosis and subsequent depletion of inositol for phosphatidylinositol synthesis may explain the anti-manic and anti-depressive effects of lithium administered to treat bipolar disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A pseudogene of this gene is also present on chromosome 8q21.13. |
Product Overview | This product is a mouse antibody against impa1. It can be used for impa1 detection in Western Blot, Enzyme-Linked Immunosorbent Assay. |
Alternative Names | MGC83403 protein; impa1; MGC83403 |
UniProt ID | Q6GM60 |
Protein Refseq | The length of the protein is 280 amino acids long. The sequence is show below: MEDRWQECMDFAVSIARKAGSVVCAALKEDVSIMVKSSPADLVTATDQKVEEMIISSIKEKYPSHSFIGEESVAAGAGSTLTDNATWIIDPIDGTTNFVHRFPFVAVSIGFAVNKQVEFGVVYSCVEDKMYTGRKGKGSFCNGQKLQVSGQKDITKSMIITELGSNRNPEVIKTVLSNMERLLCIPIHGIRAVGTAAVNMCLVATGGADAYYEMGLHCWDMAAASVIVTEAGGTILDATGGLFDLMSCRIISASSREIAERIAKELQIIPLERDDGISTN. |
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For Research Use Only | Not For Clinical Use.
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