Mouse Anti-Frog taf10 Antibody (MO-AB-08239H)


Cat: MO-AB-08239H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO08239C
SpecificityThis antibody binds to Frog taf10.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography
Cellular LocalizationNucleus

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.
Product OverviewThis product is a mouse antibody against taf10. It can be used for taf10 detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesTaf10b protein; taf10; taf10b
UniProt IDQ0IH90
Protein RefseqThe length of the protein is 196 amino acids long.
The sequence is show below: MSGTESAPDSQAAIPSIQPGPAPEIKPSPANIPKPGPVPPTAAALPARDTGERRASVPASAAAAPSEGSLSNGVYLPPGVANGDVKPVISTTPLVDFLMQLEDYTPTIPDAVTGYYLNRAGFEASDPRIIRLISLAAQKFISDIANDALQHCKMKGTASGSSRSKSKDKKYTLTMEDLTPALGEYGINVKKPHYFT.
For Research Use Only | Not For Clinical Use.
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