Mouse Anti-Frog top3a Antibody (MO-AB-08628H)


Cat: MO-AB-08628H
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Specifications

Host speciesMouse (Mus musculus)
Species ReactivityFrog (Xenopus laevis)
CloneMO08628C
SpecificityThis antibody binds to Frog top3a.
FormatLiquid or Lyophilized
StorageStore at 4°C: short-term (1-2weeks)
Store at -20°C: long-term and future use
Purity> 90% was determined by SDS-PAGE
PurificationPurified with Protein A or G affinity chromatography

Application Information

ApplicationWB, ELISA
Application NotesELISA: 1:1000-1:3000
Other applications are to be developed. The optimal dilution should be determined by the end user.

Target

IntroductionThis gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms.
Product OverviewThis product is a mouse antibody against top3a. It can be used for top3a detection in Western Blot, Enzyme-Linked Immunosorbent Assay.
Alternative NamesDNA topoisomerase; EC 5.99.1.2; top3a; MGC80537
UniProt IDQ6GPC0
Protein RefseqThe length of the protein is 1022 amino acids long.
The sequence is show below: MVILSRVLALSKFKVVLRPAVRFCSHRTAAEMALRIPVQKVLCVAEKNDAAKGIADLMSNSRMRRREGFSKFNKIYEYEYHLFGKDVTVVMTSVSGHLLALEFMDHMKKWHSCNPVSLFEAEVQKYCPDDFVNIKRTLEREVRQCQALIIWTDCDREGENIGFEIIHVCKSVKPNLQVFRARFSEITPRSIRMACEHLVQPDQNINDAVDVRTELDLRIGAAFTRFQTLRLQKIFPSVLSNQLISYGSCQFPTLGFVVERFKAIQAFIPETFYKIKVTHEHEDGLVEFSWKRNRLFNHTACLVLYQICMEDPMATVMEVGSKPKSKWRPVALDTVELEKLASRKLKIGAKETMKTAEKLYTQGFISYPRTETNIFPKDLNLTSLVEQQTHDPQWGGFAQRILERGGPTPRNGNKTDQAHPPIHPTKYTNNLQGNEQRIYEFIVRHFLACCSQDAQGQETTVEIDIAAERFVAHGLMIIARNYLDVYPYDKWNTKIIPVYEMGAQFQPTTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAEHIETIKSRSYVGLTPEQRFLPGELGMGLVEGYDSMGFQMSKPDLRAELESDLKLICEGKKDKFTVLRLQIQKYKQVFVEAAAKATKLDEALSQYFGQAAEAVPQQEIYAETPLPVRKCPQCNRDMVLKTKRDGGFFLSCVGYPSCKSSVWFPSSVLEVSRDESICSTCRPHPVHKLKLKFKRGSIPPLMPLEFVGCIGGCDETLREILDLKYLHGGNRPPQAAPRESNHLQVNQTSNRMGNSGDGRGRQPQTKTLKPPVVKPSTSRGAPPIPGNSESNEVVCNCGVAAVQLTVRKEGPNQGRPFYKCNGGACNFFLWADQEDGGGQNAPAGPSTGRPSNAFNNSRAPDSFRSGGGSNDPGSEGQAVVCMCNQPAVTRTVQKDGANKGRQFHTCSKPREQQCGYFQWADENVPPGSSSGFSGSSGGSSFSGGSGAQRNSGKKNKRSENSFSGPTAKKPRSCGICHQPGHNRTNCPQNR.
For Research Use Only | Not For Clinical Use.
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